[HTML][HTML] Nanoparticles in drug delivery: From history to therapeutic applications

O Afzal, ASA Altamimi, MS Nadeem, SI Alzarea… - Nanomaterials, 2022 - mdpi.com
Current research into the role of engineered nanoparticles in drug delivery systems (DDSs)
for medical purposes has developed numerous fascinating nanocarriers. This paper reviews …

Surface modification and endothelialization of biomaterials as potential scaffolds for vascular tissue engineering applications

X Ren, Y Feng, J Guo, H Wang, Q Li, J Yang… - Chemical Society …, 2015 - pubs.rsc.org
Surface modification and endothelialization of vascular biomaterials are common
approaches that are used to both resist the nonspecific adhesion of proteins and improve …

[HTML][HTML] Nano-based delivery of RNAi in cancer therapy

Y Xin, M Huang, WW Guo, Q Huang, L Zhang, G Jiang - Molecular cancer, 2017 - Springer
Background RNA interference (RNAi), a newly developed method in which RNA molecules
inhibit gene expression, has recently received considerable research attention. In the …

[HTML][HTML] Gene therapy in cancer treatment: why go nano?

C Roma-Rodrigues, L Rivas-García, PV Baptista… - Pharmaceutics, 2020 - mdpi.com
The proposal of gene therapy to tackle cancer development has been instrumental for the
development of novel approaches and strategies to fight this disease, but the efficacy of the …

[HTML][HTML] Nanoparticle-based therapeutic approach for diabetic wound healing

H Ezhilarasu, D Vishalli, ST Dheen, BH Bay… - Nanomaterials, 2020 - mdpi.com
Diabetes mellitus (DM) is a common endocrine disease characterized by a state of
hyperglycemia (higher level of glucose in the blood than usual). DM and its complications …

[HTML][HTML] Cancer nanomedicine: emerging strategies and therapeutic potentials

M Xu, X Han, H Xiong, Y Gao, B Xu, G Zhu, J Li - Molecules, 2023 - mdpi.com
Cancer continues to pose a severe threat to global health, making pursuing effective
treatments more critical than ever. Traditional therapies, although pivotal in managing …

[HTML][HTML] Production and clinical development of nanoparticles for gene delivery

J Chen, Z Guo, H Tian, X Chen - Molecular Therapy Methods & Clinical …, 2016 - cell.com
Gene therapy is a promising strategy for specific treatment of numerous gene-associated
human diseases by intentionally altering the gene expression in pathological cells. A …

[HTML][HTML] Non-viral in vitro gene delivery: it is now time to set the bar!

N Bono, F Ponti, D Mantovani, G Candiani - Pharmaceutics, 2020 - mdpi.com
Transfection by means of non-viral gene delivery vectors is the cornerstone of modern gene
delivery. Despite the resources poured into the development of ever more effective …

[HTML][HTML] Advances in the synthesis and application of magnetic ferrite nanoparticles for cancer therapy

SR Mokhosi, W Mdlalose, A Nhlapo, M Singh - Pharmaceutics, 2022 - mdpi.com
Cancer is among the leading causes of mortality globally, with nearly 10 million deaths in
2020. The emergence of nanotechnology has revolutionised treatment strategies in …

Calcium carbonate nanoparticles as cancer drug delivery system

S Maleki Dizaj, M Barzegar-Jalali… - Expert opinion on …, 2015 - Taylor & Francis
Introduction: Calcium carbonate (CaCO3) has broad biomedical utilizations owing to its
availability, low cost, safety, biocompatibility, pH-sensitivity and slow biodegradability …