The diverse role of the raphe 5-HTergic systems in epilepsy
H Cheng, C Gao, Q Lou, Z Chen, Y Wang - Acta Pharmacologica Sinica, 2022 - nature.com
The raphe nuclei comprise nearly all of 5-hydroxytryptaminergic (5-HTergic) neurons in the
brain and are widely acknowledged to participate in the modulation of neural …
brain and are widely acknowledged to participate in the modulation of neural …
GABAergic and glutamatergic inputs to the medulla oblongata and locus coeruleus noradrenergic pathways are critical for seizures and postictal antinociception …
M Mendonça-dos-Santos, TCT Gonçalves… - Scientific Reports, 2024 - nature.com
We investigated the participation of the nucleus of the tractus solitarius (NTS) in tonic‒clonic
seizures and postictal antinociception control mediated by NMDA receptors, the role of NTS …
seizures and postictal antinociception control mediated by NMDA receptors, the role of NTS …
[HTML][HTML] Neurotoxic lesions of the pedunculopontine tegmental nucleus impair the elaboration of postictal antinociception
RC de Oliveira, R de Oliveira, LL Falconi-Sobrinho… - Physiology & …, 2018 - Elsevier
Generalised tonic-clonic seizures, generated by abnormal neuronal hyper-activity, cause a
significant and long-lasting increase in the nociceptive threshold. The pedunculopontine …
significant and long-lasting increase in the nociceptive threshold. The pedunculopontine …
Long‑term effects of vitexin against development of pentylenetetrazole‑induced kindling in rats
DD De Oliveira, CP da Silva, LL Falconi-Sobrinho… - Acta Neurobiologiae …, 2024 - ane.pl
Evidence is provided that the glycosylated flavonoid vitexin (apigenin‑8‑C‑beta‑D‑
glucopyranoside) attenuates pentylenetetrazole (PTZ)‑induced acute tonic‑clonic seizures in …
glucopyranoside) attenuates pentylenetetrazole (PTZ)‑induced acute tonic‑clonic seizures in …
Nicotinic and muscarinic cholinergic receptors are recruited by acetylcholine-mediated neurotransmission within the locus coeruleus during the organisation of post …
RC de Oliveira, R de Oliveira, AF Biagioni… - Brain Research …, 2016 - Elsevier
Post-ictal antinociception is characterised by an increase in the nociceptive threshold that
accompanies tonic and tonic-clonic seizures (TCS). The locus coeruleus (LC) receives …
accompanies tonic and tonic-clonic seizures (TCS). The locus coeruleus (LC) receives …
The Effect of Muscarinic Receptor Modulators on the Antinociception Induced by CB2 Receptor Agonist, JWH133 in Mice
There is no published study regarding the interaction between muscarinic receptor
modulators and antinociception induced by cannabinoid receptor (CB 2) agonist. The effect …
modulators and antinociception induced by cannabinoid receptor (CB 2) agonist. The effect …
Evidence for a 5-HT6 receptor-mediated control of midbrain 5-HT neurons
J Brouard - 2016 - ora.ox.ac.uk
The dorsal raphe nucleus (DRN) contains the majority of 5-hydroxytryptamine (5-HT)-
producing neurons, whose firing is influenced by homeostatic feedback pathways …
producing neurons, whose firing is influenced by homeostatic feedback pathways …
[引用][C] Marcelo Mendonça‑dos‑Santos, Thaís Cristina Teixeira Gonçalves, Luiz Luciano Falconi‑Sobrinho, Tayllon dos Anjos‑Garcia, Ivair Matias Jr., Rithiele Cristina …
NC Coimbra - Scientific Reports, 2024