Colorectal cancer (CRC) is a major health concern with multifactorial pathophysiology
representing intense therapeutic challenges. It is well known that deregulation of …

Leber's hereditary optic neuropathy (LHON) is a common inherited mitochondrial disorder
that is characterized by the degeneration of the optic nerves, leading to vision loss. The …

Mitochondria being the central organelle for metabolism and other cell signalling pathways
have remained the topic of interest to tumour biologists. In spite of the wide acceptance of …

Smoking is a pernicious practice prevalent worldwide. It involves breathing of burnt-tobacco
fumes/smoke which comprises of numerous chemical entities posing deleterious aftermaths …

The role of mitochondria in tumorigenesis has regained much attention as it could
dysregulate cellular energetics, oxidative stress and apoptosis. However, the role of …

Objectives This study aimed to analyze the expression of miR-181b, miR-21, miR-31, and
miR-345 in actinic cheilitis with and without epithelial dysplasia and lower lip squamous cell …

Therapeutic application of induced pluripotent stem cell (iPSC) derivatives requires
comprehensive assessment of the integrity of their nuclear and mitochondrial DNA (mtDNA) …

Objectives The aim was to explore the dose-response relationship between occupational
polycyclic aromatic hydrocarbons (PAHs) exposure and mitochondrial damage in coke oven …

Saliva is an easily accessible biofluid with immense diagnostic potential in oral cancer. The
identification of potential saliva signatures for early, noninvasive detection of oral squamous …

We have identified 164 somatic mutations in mitochondrial DNA in gingivobuccal oral
cancer by deep sequencing the mitochondrial genome from paired tumor and blood DNA …