microRNA-based biomarkers in Alzheimer's disease (AD)

Y Zhao, V Jaber, PN Alexandrov, A Vergallo… - Frontiers in …, 2020 - frontiersin.org
Alzheimer's disease (AD) is a multifactorial, age-related neurological disease characterized
by complex pathophysiological dynamics taking place at multiple biological levels, including …

Sleep and depression in older adults: A narrative review

SA Nielson, DB Kay, JM Dzierzewski - Current psychiatry reports, 2023 - Springer
Abstract Purpose of Review The sleep-depression association has been recognized for
decades. Efforts to clarify this association continue at an increasing pace. This review …

Psychosocial effects of corona measures on patients with dementia, mild cognitive impairment and subjective cognitive decline

IS Van Maurik, ED Bakker, S Van den Buuse… - Frontiers in …, 2020 - frontiersin.org
Background: The recent COVID-19 pandemic is not only a major healthcare problem in
itself, but also poses enormous social challenges. Though nursing homes increasingly …

Depression as a risk factor for Alzheimer's disease: a systematic review of longitudinal meta-analyses

O Sáiz-Vázquez, P Gracia-García… - Journal of clinical …, 2021 - mdpi.com
Alzheimer's disease (AD) is the most frequent cause of dementia, linked to morbidity and
mortality among elderly patients. Recently, several clinical studies suggested that …

[HTML][HTML] Apathy symptoms, physical and cognitive function, health-related quality of life, and mortality in older patients with CKD: a longitudinal observational study

CGN Voorend, M van Buren, NC Berkhout-Byrne… - American Journal of …, 2024 - Elsevier
Rationale & Objective Apathy reflects diminished motivation, goal-directed behavior, and
emotions, as well as less engagement in social interactions. Apathy overlaps with …

Addressing depression in older adults with Alzheimer's through cognitive behavioral therapy: systematic review and meta-analysis

AM González-Martín, A Aibar Almazán… - Frontiers in Aging …, 2023 - frontiersin.org
Objectives This systematic review and meta-analysis was conducted to provide an analysis
of the published data about the effects of cognitive behavioral therapies on the depression of …

[HTML][HTML] Subjective Cognitive Impairment and Physical Activity: Investigating Risk Factors and Correlations among Older Adults in Spain

JM Franco-García, Á Denche-Zamorano… - Journal of Functional …, 2024 - mdpi.com
Subjective cognitive impairment in older persons has a substantial influence on their quality
of life and can progress to serious illnesses such as dementia. Physical activity level can …

Sleep time estimated by an actigraphy watch correlates with CSF tau in cognitively unimpaired elders: the modulatory role of APOE

S López-García, C Lage, A Pozueta… - Frontiers in aging …, 2021 - frontiersin.org
There is increasing evidence of the relationship between sleep and neurodegeneration, but
this knowledge is not incorporated into clinical practice yet. We aimed to test whether a basic …

[HTML][HTML] Potentially modifiable risk factors for dementia and mild cognitive impairment: an umbrella review and meta-analysis

A Jones, MU Ali, M Kenny, A Mayhew… - Dementia and Geriatric …, 2024 - karger.com
Introduction: The prevalence of mild and major neurocognitive disorders (NCDs), also
referred to as mild cognitive impairment and dementia, is rising globally. The prevention of …

The role of sex differences in depression in pathologically defined Alzheimer's disease

C Tremblay, P Choudhury, CM Belden… - Frontiers in Aging …, 2023 - frontiersin.org
Introduction Sex differences in Alzheimer's disease (AD) may contribute to disease
heterogeneity and affect prevalence, risk factors, disease trajectories and outcomes …