Chronic myeloid leukemia: 2018 update on diagnosis, therapy and monitoring

E Jabbour, H Kantarjian - American journal of hematology, 2018 - Wiley Online Library
Disease overview Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm with an
incidence of 1‐2 cases per 100 000 adults. It accounts for approximately 15% of newly …

Chronic myeloid leukemia: 2014 update on diagnosis, monitoring, and management

E Jabbour, H Kantarjian - American journal of hematology, 2014 - Wiley Online Library
Disease overview: Chronic Myeloid Leukemia (CML) is a myeloproliferative neoplasm with
an incidence of 1–2 cases per 100,000 adults, and accounts for∼ 15% of newly diagnosed …

Long-term benefits and risks of frontline nilotinib vs imatinib for chronic myeloid leukemia in chronic phase: 5-year update of the randomized ENESTnd trial

A Hochhaus, G Saglio, TP Hughes, RA Larson… - Leukemia, 2016 - nature.com
Abstract In the phase 3 Evaluating Nilotinib Efficacy and Safety in Clinical Trials–Newly
Diagnosed Patients (ENESTnd) study, nilotinib resulted in earlier and higher response rates …

Chronic myeloid leukemia: 2020 update on diagnosis, therapy and monitoring

E Jabbour, H Kantarjian - American journal of hematology, 2020 - Wiley Online Library
Disease overview Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm with an
incidence of 1‐2 cases per 100 000 adults. It accounts for approximately 15% of newly …

Early response with dasatinib or imatinib in chronic myeloid leukemia: 3-year follow-up from a randomized phase 3 trial (DASISION)

E Jabbour, HM Kantarjian, G Saglio… - Blood, The Journal …, 2014 - ashpublications.org
This analysis explores the impact of early cytogenetic and molecular responses on the
outcomes of patients with chronic myeloid leukemia in chronic phase (CML-CP) in the phase …

Pharmacogenomic landscape of patient-derived tumor cells informs precision oncology therapy

JK Lee, Z Liu, JK Sa, S Shin, J Wang, M Bordyuh… - Nature …, 2018 - nature.com
Outcomes of anticancer therapy vary dramatically among patients due to diverse genetic
and molecular backgrounds, highlighting extensive intertumoral heterogeneity. The …

Chronic myeloid leukemia: 2016 update on diagnosis, therapy, and monitoring

E Jabbour, H Kantarjian - American journal of hematology, 2016 - Wiley Online Library
Disease overview: Chronic Myeloid Leukemia (CML) is a myeloproliferative neoplasm with
an incidence of 1‐2 cases per 100,000 adults. It accounts for approximately 15% of newly …

The EUTOS population-based registry: incidence and clinical characteristics of 2904 CML patients in 20 European Countries

VS Hoffmann, M Baccarani, J Hasford, D Lindörfer… - Leukemia, 2015 - nature.com
This population-based registry was designed to provide robust and updated information on
the characteristics and the epidemiology of chronic myeloid leukemia (CML). All cases of …

Early molecular response predicts outcomes in patients with chronic myeloid leukemia in chronic phase treated with frontline nilotinib or imatinib

TP Hughes, G Saglio, HM Kantarjian… - Blood, The Journal …, 2014 - ashpublications.org
We explored the impact of early molecular response (EMR; BCR-ABL≤ 10% on the
international scale [BCR-ABLIS] at 3 or 6 months) on outcomes in patients with newly …

Diagnosis and treatment of chronic myeloid leukemia in 2015

PA Thompson, HM Kantarjian, JE Cortes - Mayo Clinic Proceedings, 2015 - Elsevier
Few neoplastic diseases have undergone a transformation in a relatively short period like
chronic myeloid leukemia (CML) has in the last few years. In 1960, CML was the first cancer …