Increasing evidence suggests that vascular risk factors contribute to neurodegeneration,
cognitive impairment and dementia. While there is considerable overlap between features of …

Advances in neuroimaging have enabled greater understanding of the progression of
cerebral degenerative processes associated with ageing‐related dementias. Leukoaraiosis …

Vascular cognitive impairment (VCI) or vascular dementia occurs as a result of brain
ischemia and represents the second most common type of dementia after Alzheimer's …

Environmental enrichment (EE) has been widely used as a means to enhance brain
plasticity mechanisms (eg, increased dendritic branching, synaptogenesis, etc.) and improve …

White matter (WM) disease is associated with disruption of the gliovascular unit, which
involves breach of the blood–brain barrier (BBB). We quantified pericytes as components of …

Vascular cognitive impairment (VCI) refers to all forms of cognitive disorder related to
cerebrovascular diseases, including vascular mild cognitive impairment, post-stroke …

Neurovascular unit mural cells called 'pericytes' maintain the blood-brain barrier and local
cerebral blood flow. Pathological changes in the hippocampus predispose to cognitive …

Background This study was designed to explore the beneficial effects of environmental
enrichment (EE) on white matter glial changes in a mouse model of chronic cerebral …

Environmental enrichment (EE) refers to different forms of stimulation, where the
environment is designed to improve the levels of sensory, cognitive, and motor stimuli …

Mouse models have shown that cerebral hypoperfusion causes white matter disruption and
memory impairment relevant to the study of vascular cognitive impairment and dementia …