The complex interaction of cells with biomaterials (ie, materiobiology) plays an increasingly
pivotal role in the development of novel implants, biomedical devices, and tissue …

The uterine lining (endometrium) regenerates repeatedly over the life span as part of its
normal physiology. Substantial portions of the endometrium are shed during childbirth …

Uniquely among adult tissues, the human endometrium undergoes cyclical shedding, scar-
free repair and regeneration during a woman's reproductive life. Therefore, it presents an …

The uterus is vital for successful reproduction in mammals, and two different types of
epithelia (luminal and glandular) are essential for embryo implantation and pregnancy …

Estrogen and progesterone, acting through their cognate receptors the estrogen receptor α
(ERα) and the progesterone receptor (PR) respectively, regulate uterine biology. Using rapid …

The human endometrium undergoes approximately 450 cycles of proliferation,
differentiation, shedding and regeneration over a woman's reproductive lifetime. The …

The existence and function of Lgr5+ cells within the developing esophagus remains
unknown. Here, we document multiple discrete Lgr5+ populations in the developing mouse …

The human endometrium is a remarkable tissue, undergoing approximately 450 cycles of
proliferation, differentiation, shedding (menstruation), repair and regeneration over a …

Healthy functioning of the female reproductive tract (FRT) depends on balanced and
dynamic regulation by hormones during the menstrual cycle, pregnancy and childbirth. The …

Lgr5+ crypt base columnar cells, the operational intestinal stem cells (ISCs), are thought to
be dispensable for small intestinal (SI) homeostasis. Using a Lgr5-2A-DTR (diphtheria toxin …