Spinal cord injury (SCI) is a devastating condition affecting 270,000 people in the United
States. A potential treatment for decreasing the secondary inflammation, excitotoxic damage …

For the past century, research on neurological disorders has largely focused on the most
prominently affected cell types–the neurons. However, with increasing knowledge of the …

Developing a simple produces for efficient derivation of motor neurons (MNs) is essential for
neural tissue engineering studies. Stem cells with high capacity for neural differentiation and …

Highly porous poly (ϵ-caprolactone) microfiber scaffolds can be fabricated using
electrospinning for tissue engineering applications. Melt electrospinning produces such …

Induced pluripotent cell-derived motoneurons (iPSCMNs) are sought for use in cell
replacement therapies and treatment strategies for motoneuron diseases such as …

Pluripotent stem cells (PSCs) offer unprecedented biomedical potential not only in relation to
humans but also companion animals, particularly the horse. Despite this, attempts to …

Objective Genetic modification of human embryonic stem cells (hESCs) is critical for their
extensive use as a fundamental tool for cell therapy and basic research. Despite the fact that …

Access to healthy or diseased human neural tissue is a daunting task and represents a
barrier for advancing our understanding about the cellular, genetic, and molecular …

Spinal cord injury (SCI) is a devastating condition affecting 270,000 people in the United
States. The use of growth factors is a potential treatment for reducing secondary damage …

The most important property of stem cells from different sources is the capacity to
differentiate into various cells and tissue types. However, problems including contamination …