Microvesicles and exosomes: new players in metabolic and cardiovascular disease

C Lawson, JM Vicencio, DM Yellon… - Journal of …, 2016 - joe.bioscientifica.com
The past decade has witnessed an exponential increase in the number of publications
referring to extracellular vesicles (EVs). For many years considered to be extracellular …

The gut as a sensory organ

JB Furness, LR Rivera, HJ Cho, DM Bravo… - Nature reviews …, 2013 - nature.com
The gastrointestinal tract presents the largest and most vulnerable surface to the outside
world. Simultaneously, it must be accessible and permeable to nutrients and must defend …

Teduglutide reduces need for parenteral support among patients with short bowel syndrome with intestinal failure

PB Jeppesen, M Pertkiewicz, B Messing, K Iyer… - Gastroenterology, 2012 - Elsevier
BACKGROUND & AIMS: Teduglutide, a glucagon-like peptide 2 analogue, might restore
intestinal structural and functional integrity by promoting growth of the mucosa and reducing …

The glucagon-like peptides

TJ Kieffer, J Francis Habener - Endocrine reviews, 1999 - academic.oup.com
Glucagon-Like Peptides | Endocrine Reviews | Oxford Academic Skip to Main Content
Advertisement Oxford Academic Journals Books Search Menu Information Account Menu …

Randomised placebo-controlled trial of teduglutide in reducing parenteral nutrition and/or intravenous fluid requirements in patients with short bowel syndrome

PB Jeppesen, R Gilroy, M Pertkiewicz, JP Allard… - Gut, 2011 - gut.bmj.com
Background and aims Teduglutide, a GLP-2 analogue, may restore intestinal structural and
functional integrity by promoting repair and growth of the mucosa and reducing gastric …

Physiology and pharmacology of the enteroendocrine hormone glucagon-like peptide-2

DJ Drucker, B Yusta - Annual review of physiology, 2014 - annualreviews.org
Glucagon-like peptide-2 (GLP-2) is a 33-amino-acid proglucagon-derived peptide secreted
from enteroendocrine L cells. GLP-2 circulates at low basal levels in the fasting period, and …

The role of gut adaptation in the potent effects of multiple bariatric surgeries on obesity and diabetes

RJ Seeley, AP Chambers, DA Sandoval - Cell metabolism, 2015 - cell.com
Bariatric surgical procedures such as vertical sleeve gastrectomy (VSG) and Roux-en-Y
gastric bypass (RYGB) are the most potent treatments available to produce sustained …

Gastrointestinal hormones and food intake

AD Strader, SC Woods - Gastroenterology, 2005 - Elsevier
Despite dramatic fluctuations in calorie intake, animals maintain a very stable body weight.
The reason is that energy intake and expenditure are precisely matched. Long-term …

Glucagon-like peptides

DJ Drucker - Diabetes, 1998 - Am Diabetes Assoc
Proglucagon contains the sequence of two glucagonlike peptides, GLP-1 and GLP-2,
secreted from enteroendocrine cells of the small and large intestine. GLP-1 lowers blood …

The multifunctional or moonlighting protein CD26/DPPIV

E Boonacker, CJF Van Noorden - European journal of cell biology, 2003 - Elsevier
CD26/DPPIV can be considered a moonlighting protein because it is a multifunctional
protein that exerts its different functions depending on cell type and intra-or extracellular …