Glycosylation is one of the most prevalent posttranslational modifications that profoundly
affects the structure and functions of proteins in a wide variety of biological recognition …

Polymeric materials, natural and unnatural, are indispensable to the modern society. They
are widely used from everyday life usages as commodity materials to industry and …

The endo-β-N-acetylglucosaminidases (ENGases) are an enzyme class (EC 3.2. 1.96)
produced by a range of organisms, ranging from bacteria, through fungi, to higher order …

Carbohydrates have been shown to play important roles in biological processes. The pace
of development in carbohydrate research is, however, relatively slow due to the problems …

Aims This review is intended to update our previous discussion on the chemoenzymatic
synthesis of carbohydrates and glycoconjugates,(1) with new emphasis placed on …

Remarkable advances have been made in recent years in exploiting the transglycosylation
activity of glycosidases and glycosynthase mutants for oligosaccharide and glycoconjugate …

Homogeneous N-glycoproteins carrying defined natural N-glycans are essential for detailed
structural and functional studies. The transglycosylation activity of the endo-β-N …

Chemoenzymatic transglycosylation catalyzed by endo-S mutants is a powerful tool for in
vitro glycoengineering of therapeutic antibodies. In this paper, we report a one-pot …

Protein glycosylation is a common and complex posttranslational modification of proteins,
which expands functional diversity while boosting structural heterogeneity. Glycoproteins …

Structurally well-defined IgG-Fc glycoforms are highly demanded for understanding the
effects of glycosylation on an antibody's effector functions. We report in this paper …