The diversity in the applications of partial least squares: an overview

T Mehmood, B Ahmed - Journal of Chemometrics, 2016 - Wiley Online Library
Advances in technology make it happen to have massive amount of information in the form
of multiple variables per object. The use of multivariate approaches for modeling the real‐life …

Integrating genetics and epigenetics in breast cancer: biological insights, experimental, computational methods and therapeutic potential

C Cava, G Bertoli, I Castiglioni - BMC systems biology, 2015 - Springer
Background Development of human cancer can proceed through the accumulation of
different genetic changes affecting the structure and function of the genome. Combined …

Peptides and combination of peptides for use in immunotherapy against small cell lung cancer and other cancers

M Andrea, T Weinschenk, V Goldfinger… - US Patent …, 2019 - Google Patents
The present invention relates to peptides, proteins, nucleic acids and cells for use in
immunotherapeutic methods. In particular, the present invention relates to the immuno …

Peptides and combination of peptides for use in immunotherapy against small cell lung cancer and other cancers

A Mahr, T Weinschenk, V Goldfinger, O Schoor… - 2018 - Google Patents
ZRKFYGHZFMAOKI-QMGMOQQFSA-N tgfbeta Chemical compound C ([C@ H](NC (=
O)[C@ H](C (C) C) NC (= O) CNC (= O)[C@ H](CCC (O)= O) NC (= O)[C@ H](CCCNC (N) …

Joint analysis of miRNA and mRNA expression data

A Muniategui, J Pey, FJ Planes… - Briefings in …, 2013 - academic.oup.com
Abstract miRNAs are small RNA molecules (′ 22 nt) that interact with their target mRNAs
inhibiting translation or/and cleavaging the target mRNA. This interaction is guided by …

Quantification of miRNA-mRNA interactions

A Muniategui, R Nogales-Cadenas, M Vázquez… - PloS one, 2012 - journals.plos.org
miRNAs are small RNA molecules (′ 22 nt) that interact with their corresponding target
mRNAs inhibiting the translation of the mRNA into proteins and cleaving the target mRNA …

Identification of transcriptional markers and microRNA–mRNA regulatory networks in colon cancer by integrative analysis of mRNA and microRNA expression profiles …

MN Uddin, M Li, X Wang - Cells, 2019 - mdpi.com
The aberrant expression of microRNAs (miRNAs) and genes in tumor microenvironment
(TME) has been associated with the pathogenesis of colon cancer. An integrative …

Identification of novel targets for miR-29a using miRNA proteomics

R Bargaje, S Gupta, A Sarkeshik, R Park, T Xu… - 2012 - journals.plos.org
MicroRNAs (miRNAs) are short regulatory RNA molecules that interfere with the expression
of target mRNA by binding to complementary sequences. Currently, the most common …

[图书][B] Computational biology and bioinformatics: gene regulation

KC Wong - 2016 - books.google.com
This book presents the latest research in computational biology and bioinformatics, with a
thematic focus on gene regulation. It is designed to be self-contained and comprehensive …

Integrated ordination of miRNA and mRNA expression profiles

G Diaz, F Zamboni, A Tice, P Farci - BMC genomics, 2015 - Springer
Background Several studies have investigated miRNA and mRNA co-expression to identify
regulatory networks at the transcriptional level. A typical finding of these studies is the …