Dipeptidyl-peptidase IV/CD26 (DPP IV) is a cell-surface protease belonging to the
prolyloligopeptidase family. It selectively removes the N-terminal dipeptide from peptides …

During the past decade, proof of the principle that peptide receptors can be used
successfully for in vivo targeting of human cancers has been provided. The molecular basis …

Over the past 20 years, abundant evidence has been collected to suggest that gastrin-
releasing peptide (GRP) and its receptors play an important role in the development of a …

Certain serine proteases signal to cells by cleaving protease-activated receptors (PARs) and
thereby regulate hemostasis, inflammation, pain and healing. However, in many tissues the …

This following article is written for Prof. Abba Kastin's Festschrift, to add to the tribute to his
important role in the advancement of the role of peptides in physiological, as well as …

Currently available techniques for performing quantitative immunohistochemistry (Q-IHC)
rely upon pixel-counting algorithms and therefore cannot provide information as to the …

Objective: To evaluate the effect of bombesin (BBS) and neurotensin (NT) on intestinal
histopathology, intestinal oxidative stress, and endotoxemia in experimental obstructive …

Epithelial cells lining the adult human colon do not normally express gastrin-releasing
peptide (GRP) or its receptor (GRPR). In contrast, approximately one-third of human colon …

Bombesin is a tetradecapeptide neurohormone that binds to gastrin-releasing peptide
receptors (GRPR). GRPRs have been found in a variety of cancers including invasive breast …

Prostate cancer is one of the most common causes of cancer in men. Evaluating the different
stages of prostate cancer with conventional imaging techniques still proves difficult. Nuclear …