Abstract The US Food and Drug Administration (FDA) has publicly recognized the
importance of improving drug development efficiency, deeming translational biomarkers a …

Motor deficits typical of Parkinson's disease (PD), such as gait and balance disturbances,
tremor, reduced arm swing and finger movement, and voice and breathing changes, are …

Smartphones and wearables are widely recognised as the foundation for novel Digital
Health Technologies (DHTs) for the clinical assessment of Parkinson's disease. Yet, only …

Parkinson disease (PD) is a complex neurodegenerative disorder that afflicts over 10 million
people worldwide, resulting in debilitating motor and cognitive impairment. In the United …

Prevalence estimates of Parkinson's disease (PD)—the fastest-growing neurodegenerative
disease—are generally underestimated due to issues surrounding diagnostic accuracy …

The increased use of sensor‐based digital health technologies (DHTs) in clinical trials
brought to light concerns about implementation practices that might introduce burden on trial …

In the field of smart healthcare, wearable and sensing devices are connected to the Internet
of Things (IoT) to assess patients within their own homes. Fatigue is a multidimensional …

Background Light exposure significantly impacts human health, regulating our circadian
clock, sleep–wake cycle and other physiological processes. With the emergence of …

Digital health technologies have the potential to measure how a patient feels and functions
with low patient burden eg: to provide real-world evidence of the benefit of a novel treatment …

Digital health technologies (DHT) such as wearables, mobile devices and home-based
sensing systems are poised to deliver precise, convenient, remote monitoring solutions to …