Liquid biopsy for cancer: review and implications for the radiologist

JJ Underwood, RS Quadri, SP Kalva, H Shah… - Radiology, 2020 - pubs.rsna.org
Imaging and image-guided procedures play an imperative role in the screening, diagnosis,
and surveillance of cancer. Although emerging imaging techniques now enable more …

Exosomes in the lung cancer microenvironment: Biological functions and potential use as clinical biomarkers

R Qi, Y Zhao, Q Guo, X Mi, M Cheng, W Hou… - Cancer Cell …, 2021 - Springer
Lung cancer is one of the most common malignant tumours worldwide. however, emerging
immunotherapy and targeted therapies continue to show limited efficacy. In the search for …

[HTML][HTML] Blood first assay screening trial (BFAST) in treatment-naive advanced or metastatic NSCLC: initial results of the phase 2 ALK-positive cohort

R Dziadziuszko, T Mok, S Peters, JY Han… - Journal of Thoracic …, 2021 - Elsevier
Abstract Introduction The Blood First Assay Screening Trial is an ongoing open-label,
multicohort study, prospectively evaluating the relationship between blood-based next …

[HTML][HTML] Comparison of solid tissue sequencing and liquid biopsy accuracy in identification of clinically relevant gene mutations and rearrangements in lung …

LH Lin, DHR Allison, Y Feng, G Jour, K Park, F Zhou… - Modern Pathology, 2021 - Elsevier
Screening for therapeutic targets is standard of care in the management of advanced non-
small cell lung cancer. However, most molecular assays utilize tumor tissue, which may not …

Unique genomic alterations of cerebrospinal fluid cell-free DNA are critical for targeted therapy of non-small cell lung cancer with leptomeningeal metastasis

Y Wang, F Jiang, R Xia, M Li, C Yao, Y Li, H Li… - Frontiers in …, 2021 - frontiersin.org
We reported unique molecular features of cerebrospinal fluid (CSF) of nonsmall cell lung
cancer (NSCLC) patients with leptomeningeal metastasis (LM), suggesting establishing CSF …

Beyond tissue biopsy: a diagnostic framework to address tumor heterogeneity in lung cancer

W Voigt, C Manegold, L Pilz, YL Wu… - Current opinion in …, 2020 - journals.lww.com
To augment the potential of precision therapy, improved diagnostic characterization of
tumors is pivotal. We suggest a comprehensive diagnostic framework combining tissue and …

[HTML][HTML] Potentialities and critical issues of liquid biopsy in clinical practice: An umbrella review

N Veronese, C Luchini, S Ciriminna, K Spinelli… - Translational …, 2025 - Elsevier
Background Liquid biopsy (LB) is a laboratory test performed on a fluid sample aiming at
analyzing molecular data derived from circulating cells and related entities, or from nucleic …

[HTML][HTML] Gene alterations in paired supernatants and precipitates from malignant pleural effusions of non-squamous non-small cell lung cancer

J Li, X Li, W Wang, Y Shao, Y Zhang, Z Song - Translational Oncology, 2020 - Elsevier
OBJECTIVE: This study investigated the feasibility of using malignant pleural effusion (MPE)
supernatant and paired cell blocks (precipitate) for gene profiling in patients with non-small …

Routine Molecular Screening of Patients with Advanced Non-SmallCell Lung Cancer in Circulating Cell-Free DNA at Diagnosis and During Progression Using …

J Garcia, A Gauthier, G Lescuyer, D Barthelemy… - Molecular Diagnosis & …, 2021 - Springer
Abstract Background and Objectives The use of ultra-sensitive diagnostic tests to detect
clinically actionable somatic alterations within the gene encoding the epidermal growth …

Determination of breath isoprene in 109 suspected lung cancer patients using cavity ringdown spectroscopy

X Wei, Q Li, Y Wu, J Li, G Zhang, M Sun… - Journal of Innovative …, 2022 - World Scientific
Background: Lung cancer is one of the most common malignant tumors worldwide.
Currently, effective screening methods for early lung cancer are still scarce. Breath analysis …