Mitochondria are crucial organelles responsible for energy generation in eukaryotic cells.
Oxidative stress, calcium disorders, and mitochondrial DNA abnormalities can all cause …

Auto-inflammatory and autoimmune diseases of the musculoskeletal system can be
perceived as a spectrum of rheumatic diseases, with the joints and connective tissues are …

Synovial fluid (SF) extracellular vesicles (EVs) play a pathogenic role in osteoarthritis (OA).
However, the surface markers, cell and tissue origins, and effectors of these EVs are largely …

Tissue repair is negatively affected by advanced age. Recent evidence indicates that
hematopoietic cell‐derived extracellular vesicles (EVs) are modulators of regenerative …

Background Intra-articular injection of platelet-rich plasma (PRP) or isometric contraction of
quadriceps (ICQ) has shown positive effects in patients with knee osteoarthritis (KOA) …

Purpose This study aimed to identify independent risk factors for immediate postoperative
deep vein thrombosis (DVT) in patients with open wedge high tibial osteotomy (OWHTO) …

Osteoarthritis (OA) is the most common age-related joint disease, characterized by chronic
inflammation, progressive articular cartilage destruction and subchondral osteosclerosis …

Background Emerging evidence suggests that extracellular vesicles (EVs) can play roles in
inflammatory processes and joint degradation in primary osteoarthritis (OA), a common age …

Human umbilical cord mesenchymal stem cells (UCMSCs) are a novel stem-cell source to
treat osteoarthritis (OA). Here we investigated the therapeutic effects of UCMSCs injection …

Primary afferent nociceptors can “listen” to immune cells by sensing cytokines that are
released at the site of acute inflammation or maintained inflammatory processes in case of …