The risks of long-term use of proton pump inhibitors: a critical review

M Jaynes, AB Kumar - Therapeutic advances in drug safety, 2019 - journals.sagepub.com
Proton pump inhibitors (PPIs) are among the most frequently prescribed medications. Their
use is likely even higher than estimated due to an increase in the number of PPIs available …

[HTML][HTML] Proton pump inhibitors therapy and risk of Clostridium difficile infection: Systematic review and meta-analysis

A Trifan, C Stanciu, I Girleanu, OC Stoica… - World journal of …, 2017 - ncbi.nlm.nih.gov
AIM To perform a systematic review and meta-analysis on proton pump inhibitors (PPIs)
therapy and the risk of Clostridium difficile infection (CDI). METHODS We conducted a …

Effects of gastroprotectant drugs for the prevention and treatment of peptic ulcer disease and its complications: a meta-analysis of randomised trials

B Scally, JR Emberson, E Spata, C Reith… - The Lancet …, 2018 - thelancet.com
Background Gastroprotectant drugs are used for the prevention and treatment of peptic ulcer
disease and might reduce its associated complications, but reliable estimates of the effects …

[HTML][HTML] Advantages and disadvantages of long-term proton pump inhibitor use

Y Kinoshita, N Ishimura, S Ishihara - … of neurogastroenterology and …, 2018 - ncbi.nlm.nih.gov
Proton pump inhibitors (PPIs) potently inhibit gastric acid secretion and are widely used for
treatment of acid-related diseases including gastroesophageal reflux disease and …

Adverse effects of proton-pump inhibitor use in older adults: a review of the evidence

ML Maes, DR Fixen… - Therapeutic advances in …, 2017 - journals.sagepub.com
Proton-pump inhibitors (PPIs) are a widely prescribed class of medications used to treat acid-
related disorders and use has significantly increased over the last few decades. PPIs are …

Proton pump inhibitors: risks of long‐term use

LH Eusebi, S Rabitti, ML Artesiani… - Journal of …, 2017 - Wiley Online Library
Proton pump inhibitors are among the most commonly prescribed classes of drugs, and their
use is increasing, in particular for long‐term treatment, often being over‐prescribed and …

Drug-induced acute kidney injury

MA Perazella, MH Rosner - … Journal of the American Society of …, 2022 - journals.lww.com
Medications are a common cause of AKI, especially for patients admitted to hospital wards
and the intensive care unit. Although drug-related kidney injury occurs through different …

The association between proton pump inhibitor use and the risk of adverse kidney outcomes: a systematic review and meta-analysis

S Nochaiwong, C Ruengorn, R Awiphan… - Nephrology Dialysis …, 2018 - academic.oup.com
Background Existing epidemiological studies illustrate that proton pump inhibitors (PPIs)
may be related to adverse kidney outcomes. To date, no comprehensive meta-analysis has …

Association between proton pump inhibitor use and risk of progression of chronic kidney disease

DCF Klatte, A Gasparini, H Xu, P de Deco, M Trevisan… - Gastroenterology, 2017 - Elsevier
Background & Aims Proton pump inhibitors (PPI) have been associated with acute kidney
injury and recent studies suggest that they may be associated with the risk of chronic kidney …

Proton pump inhibitors and the kidney: implications of current evidence for clinical practice and when and how to deprescribe

Z Al-Aly, G Maddukuri, Y Xie - American Journal of Kidney Diseases, 2020 - Elsevier
Proton pump inhibitors (PPIs), long thought to be safe, are associated with a number of
nonkidney adverse health outcomes and several untoward kidney outcomes, including …