Mesenchymal stem cells (MSCs) have been extensively investigated for the treatment of
various diseases. The therapeutic potential of MSCs is attributed to complex cellular and …

Mesenchymal stem cells (MSCs) are isolated from multiple biological tissues—adult bone
marrow and adipose tissues and neonatal tissues such as umbilical cord and placenta. In …

Brain Derived Neurotrophic Factor (BDNF) is a key molecule involved in plastic changes
related to learning and memory. The expression of BDNF is highly regulated, and can lead …

Astrocytes are the most abundant cell type within the central nervous system. They play
essential roles in maintaining normal brain function, as they are a critical structural and …

OBJECT Transplanted multipotent mesenchymal stromal cells (MSCs) improve functional
recovery in rats after traumatic brain injury (TBI). In this study the authors tested a novel …

Multipotent human bone marrow derived mesenchymal stem cells (hMSCs) improve
functional outcome after experimental traumatic brain injury (TBI). The present study was …

Extracellular vesicles (EVs) secreted by cells present an attractive strategy for developing
new therapies, but progress in the field is limited by several issues: The quality of the EVs …

Mesenchymal stem/stromal cells (MSCs) comprise a heterogeneous population of cells with
multilineage differentiation potential, the ability to modulate oxidative stress, and secrete …

Traumatic brain injury (TBI) remains a major cause of death and disability worldwide.
Increasing evidence indicates that TBI is an important risk factor for neurodegenerative …

The amniotic membrane (Amnio-M) has various applications in regenerative medicine. It
acts as a highly biocompatible natural scaffold and as a source of several types of stem cells …