Pharmacological properties and molecular mechanisms of thymol: prospects for its therapeutic potential and pharmaceutical development

MF Nagoor Meeran, H Javed, H Al Taee… - Frontiers in …, 2017 - frontiersin.org
Thymol, chemically known as 2-isopropyl-5-methylphenol is a colorless crystalline
monoterpene phenol. It is one of the most important dietary constituents in thyme species …

[HTML][HTML] Natural products: A hope for glioblastoma patients

R Vengoji, MA Macha, SK Batra, NA Shonka - Oncotarget, 2018 - ncbi.nlm.nih.gov
Glioblastoma (GBM) is one of the most aggressive malignant tumors with an overall dismal
survival averaging one year despite multimodality therapeutic interventions including …

Solid-lipid nanoparticles (SLN)s containing Zataria multiflora essential oil with no-cytotoxicity and potent repellent activity against Anopheles stephensi

HR Kelidari, MD Moemenbellah-Fard… - Journal of Parasitic …, 2021 - Springer
Malaria is still a global health concern with more than 400,000 death annually. Personal
protection using mosquitoes' repellent is an effective prevention strategy, especially in …

Molecular targets for combined therapeutic strategies to limit glioblastoma cell migration and invasion

AJ Yool, S Ramesh - Frontiers in pharmacology, 2020 - frontiersin.org
The highly invasive nature of glioblastoma imposes poor prospects for patient survival.
Molecular evidence indicates glioblastoma cells undergo an intriguing expansion of …

Sinularin induces oxidative stress-mediated apoptosis and mitochondrial dysfunction, and inhibits angiogenesis in glioblastoma cells

SY Hsu, ZH Wen, PC Shih, HM Kuo, SC Lin, HT Liu… - Antioxidants, 2022 - mdpi.com
Glioblastoma multiforme (GBM) is a cancer of largely unknown cause that leads to a 5-year
survival rate of approximately 7% in the United States. Current treatment strategies are not …

The anticancer effects of thymol on HepG2 cell line

F Altintas, M Tunc-Ata, M Secme, V Kucukatay - Medical Oncology, 2023 - Springer
There is an increasing incidence of liver cancer, which is a hazard for global health. The
present study was designed to evaluate possible cytotoxic, genotoxic, apoptotic, oxidant and …

The effect of Zataria multiflora on pulmonary function tests, hematological and oxidant/antioxidant parameters in sulfur mustard exposed veterans, a randomized …

MR Khazdair, O Rajabi, M Balali-Mood… - Environmental …, 2018 - Elsevier
Background Sulfur mustard is an alkylating agent which cause to short and long term
incapacitations on various organs including lung. There is no definite treatment for lung …

[HTML][HTML] Zataria multiflora ameliorates cisplatin-induced testicular damage via suppression of oxidative stress and apoptosis in a mice model

S Karimi, SJ Hosseinimehr… - Iranian Journal of …, 2018 - ncbi.nlm.nih.gov
Objective (s): Cisplatin (CP), as an anti-neoplastic drug, causes testicular damage. Zataria
multiflora Boiss (ZM), a medicinal plant, has antioxidant and anti-inflammatory properties …

The effectiveness of Zataria extract mouthwash for the management of radiation-induced oral mucositis in patients: a randomized placebo-controlled double-blind …

A Aghamohammadi, D Moslemi, J Akbari… - Clinical Oral …, 2018 - Springer
Objectives Oral mucositis (OM) is a common debilitating complication of chemoradiotherapy
treatment of head and neck cancers. This randomized placebo-controlled double-blind …

Review of natural product‐derived compounds as potent antiglioblastoma drugs

MN Park, HS Song, M Kim, MJ Lee… - BioMed research …, 2017 - Wiley Online Library
Common care for glioblastoma multiforme (GBM) is a surgical resection followed by
radiotherapy and temozolomide‐(TMZ‐) based chemotherapy. Unfortunately, these …