Summary von Willebrand disease (VWD) is a bleeding disorder caused by inherited defects
in the concentration, structure, or function of von Willebrand factor (VWF). VWD is classified …

The common autosomally inherited mucocutaneous bleeding disorder, von Willebrand
disease (VWD) results from quantitative or qualitative defects in plasma von Willebrand …

von Willebrand disease (VWD) is a commonly encountered inherited bleeding disorder
affecting both males and females, causing mucous membrane and skin bleeding symptoms …

Type 1 von Willebrand disease (VWD) is characterized by a personal and family history of
bleeding coincident with reduced levels of normal plasma von Willebrand factor (VWF). The …

Critical clinical questions remain unanswered regarding diagnosis and management of
patients with low von Willebrand factor (VWF) levels (30-50 IU/dL). To address these …

An essential guide to this major contemporary issue, Consanguinity in Context is a uniquely
comprehensive account of intra-familial marriage. Detailed information on past and present …

Safety and pharmacokinetics (PK) of recombinant von Willebrand factor (rVWF) combined at
a fixed ratio with recombinant factor VIII (rFVIII) were investigated in 32 subjects with type 3 …

Inherited deficiencies of plasma proteins involved in blood coagulation generally lead to
lifelong bleeding disorders, whose severity is inversely proportional to the degree of factor …

Forty families diagnosed by UK centres to have type 1 VWD were recruited. Following
review, six families were re-diagnosed to have type 2 VWD, one to have a platelet storage …

The development of alloantibodies against von Willebrand factor (VWF) represents a rare
but serious complication of treatment of von Willebrand disease (VWD), occurring in∼ 5% to …