Toward a science of computational ethology

DJ Anderson, P Perona - Neuron, 2014 - cell.com
The new field of" Computational Ethology" is made possible by advances in technology,
mathematics, and engineering that allow scientists to automate the measurement and the …

Caenorhabditis elegans: An Emerging Model in Biomedical and Environmental Toxicology

MCK Leung, PL Williams, A Benedetto… - Toxicological …, 2008 - academic.oup.com
The nematode Caenorhabditis elegans has emerged as an important animal model in
various fields including neurobiology, developmental biology, and genetics. Characteristics …

High-throughput behavioral analysis in C. elegans

NA Swierczek, AC Giles, CH Rankin, RA Kerr - Nature methods, 2011 - nature.com
We designed a real-time computer vision system, the Multi-Worm Tracker (MWT), which can
simultaneously quantify the behavior of dozens of Caenorhabditis elegans on a Petri plate at …

The Parallel Worm Tracker: a platform for measuring average speed and drug-induced paralysis in nematodes

D Ramot, BE Johnson, TL Berry Jr, L Carnell… - PloS one, 2008 - journals.plos.org
Background Caenorhabditis elegans locomotion is a simple behavior that has been widely
used to dissect genetic components of behavior, synaptic transmission, and muscle function …

A microfluidic platform for high-sensitivity, real-time drug screening on C. elegans and parasitic nematodes

JA Carr, A Parashar, R Gibson, AP Robertson… - Lab on a Chip, 2011 - pubs.rsc.org
This paper describes a new microfluidic platform for screening drugs and their dose
response on the locomotion behavior of free living nematodes and parasitic nematodes. The …

Disruption of mitochondrial dynamics affects behaviour and lifespan in Caenorhabditis elegans

JJ Byrne, MS Soh, G Chandhok… - Cellular and Molecular …, 2019 - Springer
Mitochondria are essential components of eukaryotic cells, carrying out critical physiological
processes that include energy production and calcium buffering. Consequently …

Chemistry and the Worm: Caenorhabditis elegans as a Platform for Integrating Chemical and Biological Research

SE Hulme, GM Whitesides - Angewandte Chemie International …, 2011 - Wiley Online Library
This Review discusses the potential usefulness of the worm Caenorhabditis elegans as a
model organism for chemists interested in studying living systems. C. elegans, a 1 mm long …

[HTML][HTML] Keeping track of worm trackers

SJ Husson, WS Costa, C Schmitt… - WormBook: The Online …, 2018 - ncbi.nlm.nih.gov
C. elegans is used extensively as a model system in the neurosciences due to its well
defined nervous system. However, the seeming simplicity of this nervous system in …

Visible light reduces C. elegans longevity

CD De Magalhaes Filho, B Henriquez, NE Seah… - Nature …, 2018 - nature.com
The transparent nematode Caenorhabditis elegans can sense UV and blue-violet light to
alter behavior. Because high-dose UV and blue-violet light are not a common feature …

Phosphoglycolate phosphatase homologs act as glycerol-3-phosphate phosphatase to control stress and healthspan in C. elegans

E Possik, C Schmitt, A Al-Mass, Y Bai, L Côté… - Nature …, 2022 - nature.com
Metabolic stress due to nutrient excess and lipid accumulation is at the root of many age-
associated disorders and the identification of therapeutic targets that mimic the beneficial …