The liver has the ability to repair itself after injury; however, a variety of pathological changes
in the liver can affect its ability to regenerate, and this could lead to liver failure …

Organ fibrosis is a process in which cellular homeostasis is disrupted and extracellular
matrix is excessively deposited. Fibrosis can lead to vital organ failure and there are no …

Background Kidney insults due to various pathogenic factors, such as trauma, infection, and
inflammation, can cause tubular epithelial cell injury and death, leading to acute kidney …

Background Renal tubular epithelial–myofibroblast transdifferentiation (EMT) plays a key
role in the regulation of renal fibrosis. Exosomes derived from human umbilical cord …

Abstract Background Systemic sclerosis (SSc) is a disease that features severe fibrosis of
the skin and lacks effective therapy. Bone marrow mesenchymal stem cell (BMSC)-derived …

Epithelial–mesenchymal transition (EMT) is an important biological process contributing to
kidney fibrosis and chronic kidney disease. This process is characterized by decreased …

Evidence has shown that mesenchymal stem cells'(MSCs) therapy has potential application
in treating chronic kidney disease (CKD). In addition, MSCs-derived exosomes can improve …

Renal fibrosis commonly leads to glomerulosclerosis and renal interstitial fibrosis and the
main pathological basis involves tubular atrophy and the abnormal increase and excessive …

There are several conditions that lead to female infertility, where traditional or conventional
treatments have limited efficacy. In these challenging scenarios, stem cell (SC) therapies …

Tissue fibrosis is characterized by excessive deposition of extracellular matrix (ECM)
components that result from the disruption of regulatory processes responsible for ECM …