Objectives To conduct an updated, systematic review of the clinical literature, classify studies
based on the strength of research design, and derive consensual, evidence-based clinical …

This is the first systematic review of reviews to assess the effect of obesity and weight loss on
health‐related quality of life (HRQoL). We identified 12 meta‐analyses/systematic reviews …

Background There is a need for valid self-report measures of core health-related quality of
life (HRQoL) domains. Objective To derive brief, reliable and valid health profile measures …

Medicine has been personal long before the concept of “personalized medicine” became
popular. Health professionals have always taken into consideration the individual …

Purpose An essential aspect of patient-centered outcomes research (PCOR) and
comparative effectiveness research (CER) is the integration of patient perspectives and …

Abstract Patient-reported outcomes (PROs), such as symptoms, health-related quality of life
(HRQOL), or patient perceived health status, are reported directly by the patient and are …

Objective To explore medication-related burden (MRB) and patients' lived experience with
medicines (PLEM) without regard to particular medication therapies or medical conditions …

Abstract Background The National Cancer Institute's Symptom Management and Health-
Related Quality of Life Steering Committee held a clinical trials planning meeting …

Total joint arthroplasty is performed to decreased pain, restore function and productivity and
improve quality of life. One-year implant survivorship following surgery is nearly 100%; …

Patient-centered outcomes research (PCOR) aims to improve care quality and patient
outcomes by providing information that patients, clinicians, and family members need …