The comet assay is a versatile, reliable, cost-efficient, and fast technique for detecting DNA
damage and repair in any tissue. It is useable in almost any cell type and applicable to both …

Abstract The International Comet Assay Workshops are a series of scientific conferences
dealing with practical and theoretical aspects of the Comet Assay (single-cell gel …

In this study, we describe the synthesis and characterization of silver nanoparticles (Ag-NPs)
of different sizes and evaluated their antibacterial activity. Particles size and morphology …

Breast cancer is the most common malignancy in women. Radiotherapy is frequently used in
patients with breast cancer, but some patients may be more susceptible to ionizing radiation …

The alkaline comet assay (single cell gel electrophoresis) is the most widely used method
for measuring DNA damage in eukaryotic cells (Neri et al., 2015). It detects strand breaks …

Purpose: Alterations in DNA damage repair (DDR) genes produce therapeutic biomarkers.
However, the characteristics and significance of DDR alterations remain undefined in …

(1) In compliance with the 3Rs policy to reduce, refine and replace animal experiments, the
development of advanced in vitro models is needed for nanotoxicity assessment. Cells …

Radical oxygen species formed in human tissue cells by many endogenous and exogenous
pathways cause extensive oxidative damage which has been linked to various human …

Health authorities are alarmed worldwide about the increase of obesity and overweight in
the last decades which lead to adverse health effects including inflammation, cancer …

This optimized protocol (including links to instruction videos) describes a comet-based in
vitro DNA repair assay that is relatively simple, versatile, and inexpensive, enabling the …