Activity‐based NIR enzyme fluorescent probes for the diagnosis of tumors and image‐guided surgery

H Li, D Kim, Q Yao, H Ge, J Chung, J Fan… - Angewandte …, 2021 - Wiley Online Library
Near‐infrared (NIR) activatable fluorescent probes have been considered to be the effective
edge tools for the investigation of cell biology and disease diagnosis because of their …

Tumour budding in solid cancers

A Lugli, I Zlobec, MD Berger, R Kirsch… - Nature Reviews Clinical …, 2021 - nature.com
Tumour budding is an emerging prognostic biomarker in colorectal cancer (CRC) and other
solid cancers. Tumour buds are usually defined as isolated single cancer cells or clusters of …

[HTML][HTML] Recommendations for reporting tumor budding in colorectal cancer based on the International Tumor Budding Consensus Conference (ITBCC) 2016

A Lugli, R Kirsch, Y Ajioka, F Bosman, G Cathomas… - Modern pathology, 2017 - Elsevier
Tumor budding is a well-established independent prognostic factor in colorectal cancer but
a standardized method for its assessment has been lacking. The primary aim of the …

World Endoscopy Organization consensus statements on post-colonoscopy and post-imaging colorectal cancer

MD Rutter, I Beintaris, R Valori, HM Chiu, DA Corley… - Gastroenterology, 2018 - Elsevier
Background & Aims Colonoscopy examination does not always detect colorectal cancer
(CRC)—some patients develop CRC after negative findings from an examination. When this …

Tumor budding: the name is EMT. Partial EMT.

AD Grigore, MK Jolly, D Jia, MC Farach-Carson… - Journal of clinical …, 2016 - mdpi.com
Tumor budding is a histological phenomenon encountered in various cancers, whereby
individual malignant cells and/or small clusters of malignant cells are seen in the tumor …

Tumor budding in colorectal cancer—ready for diagnostic practice?

VH Koelzer, I Zlobec, A Lugli - Human pathology, 2016 - Elsevier
Tumor budding is an important additional prognostic factor for patients with colorectal cancer
(CRC). Defined as the presence of single tumor cells or small clusters of up to 5 cells in the …

Tumor budding is an independent prognostic marker in early stage oral squamous cell carcinoma: With special reference to the mode of invasion and worst pattern of …

S Shimizu, A Miyazaki, T Sonoda, K Koike, K Ogi… - PloS one, 2018 - journals.plos.org
Pathologically proven regional lymph node metastasis affects the prognosis in early stage
oral cancer. Therefore we investigated invasive tumor patterns predicting nodal involvement …

Improving tumor budding reporting in colorectal cancer: a Delphi consensus study

TS Haddad, A Lugli, S Aherne, V Barresi, B Terris… - Virchows Archiv, 2021 - Springer
Tumor budding is a long-established independent adverse prognostic marker in colorectal
cancer, yet methods for its assessment have varied widely. In an effort to standardize its …

Automated analysis of lymphocytic infiltration, tumor budding, and their spatial relationship improves prognostic accuracy in colorectal cancer

IP Nearchou, K Lillard, CG Gavriel, H Ueno… - Cancer immunology …, 2019 - AACR
Both immune profiling and tumor budding significantly correlate with colorectal cancer
patient outcome but are traditionally reported independently. This study evaluated the …

Tumour budding in colorectal cancer: what do we know and what can we do?

L De Smedt, S Palmans, X Sagaert - Virchows Archiv, 2016 - Springer
Budding is a process during which individual or small clusters of up to five tumour cells
detach from the main tumour mass and invade into the surrounding stroma. In colorectal …