Oxidized low-density lipoprotein as a biomarker of cardiovascular diseases

A Trpkovic, I Resanovic, J Stanimirovic… - Critical reviews in …, 2015 - Taylor & Francis
Atherosclerosis is a life-long illness that begins with risk factors, which in turn contribute to
the development of subclinical disease, followed by the establishment of overt …

American Society of Echocardiography recommendations for use of echocardiography in clinical trials: a report from the american society of echocardiography's …

JS Gottdiener, J Bednarz, R Devereux… - Journal of the …, 2004 - onlinejase.com
Echocardiography is one of the most commonly performed noninvasive diagnostic tests in
patients with known or suspected cardiovascular diseases. Echocardiography provides …

Role of Lipoprotein-Associated Phospholipase A2 in Atherosclerosis: Biology, Epidemiology, and Possible Therapeutic Target

A Zalewski, C Macphee - Arteriosclerosis, thrombosis, and …, 2005 - Am Heart Assoc
The development of atherosclerotic vascular disease is invariably linked to the formation of
bioactive lipid mediators and accompanying vascular inflammation. Lipoprotein-associated …

[HTML][HTML] Endothelial dysfunction in COVID-19: Current findings and therapeutic implications

MP Nägele, B Haubner, FC Tanner, F Ruschitzka… - Atherosclerosis, 2020 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) increases the risk of several non-pulmonary
complications such as acute myocardial injury, renal failure or thromboembolic events. A …

Oxidized phospholipids in cardiovascular disease

S Tsimikas, JL Witztum - Nature Reviews Cardiology, 2024 - nature.com
Prolonged or excessive exposure to oxidized phospholipids (OxPLs) generates chronic
inflammation. OxPLs are present in atherosclerotic lesions and can be detected in plasma …

C-reactive protein and other emerging blood biomarkers to optimize risk stratification of vulnerable patients

S Tsimikas, JT Willerson, PM Ridker - Journal of the American College of …, 2006 - jacc.org
Several emerging plasma biomarkers may ultimately prove useful in risk stratification and
prognosis of cardiovascular disease. The clinical utility of these biomarkers will depend on …

Lipoprotein (a) and carotid intima-media thickness in children with familial hypercholesterolaemia in the Netherlands: a 20-year follow-up study

LM de Boer, A Wiegman, J Kroon… - The lancet Diabetes & …, 2023 - thelancet.com
Background Elevated lipoprotein (a) and familial hypercholesterolaemia are both
independent risk conditions for cardiovascular disease. Although signs of atherosclerosis …

COVID‐19 and Acute Coronary Syndromes: From Pathophysiology to Clinical Perspectives

L Esposito, FP Cancro, A Silverio… - Oxidative medicine …, 2021 - Wiley Online Library
Acute coronary syndromes (ACS) are frequently reported in patients with coronavirus
disease 2019 (COVID‐19) and may impact patient clinical course and mortality. Although …

High-dose atorvastatin reduces total plasma levels of oxidized phospholipids and immune complexes present on apolipoprotein B-100 in patients with acute coronary …

S Tsimikas, JL Witztum, ER Miller, WJ Sasiela… - Circulation, 2004 - Am Heart Assoc
Background—Oxidized phospholipids (OxPL) are present within atherosclerotic plaques
and bound by lipoprotein (a)[Lp (a)] in plasma. This study evaluated the impact of …

Early statin therapy restores endothelial function in children with familial hypercholesterolemia

S de Jongh, MR Lilien, J op't Roodt, ESG Stroes… - Journal of the American …, 2002 - jacc.org
Objectives: This study was designed to determine whether simvastatin improves endothelial
function in children with familial hypercholesterolemia (FH). Background: Endothelial …