Artificial intelligence for COVID-19 drug discovery and vaccine development

A Keshavarzi Arshadi, J Webb, M Salem… - Frontiers in Artificial …, 2020 - frontiersin.org
SARS-COV-2 has roused the scientific community with a call to action to combat the growing
pandemic. At the time of this writing, there are as yet no novel antiviral agents or approved …

Immunoinformatics and vaccine development: an overview

AN Oli, WO Obialor, MO Ifeanyichukwu… - ImmunoTargets and …, 2020 - Taylor & Francis
The use of vaccines have resulted in a remarkable improvement in global health. It has
saved several lives, reduced treatment costs and raised the quality of animal and human …

Identification of vaccine targets in pathogens and design of a vaccine using computational approaches

K Rawal, R Sinha, BA Abbasi, A Chaudhary, SK Nath… - Scientific reports, 2021 - nature.com
Antigen identification is an important step in the vaccine development process.
Computational approaches including deep learning systems can play an important role in …

Immunoinformatics design of a novel epitope-based vaccine candidate against dengue virus

AO Fadaka, NRS Sibuyi, DR Martin, M Goboza… - Scientific reports, 2021 - nature.com
Dengue poses a global health threat, which will persist without therapeutic intervention.
Immunity induced by exposure to one serotype does not confer long-term protection against …

A guide to current methodology and usage of reverse vaccinology towards in silico vaccine discovery

SJ Goodswen, PJ Kennedy… - FEMS Microbiology …, 2023 - academic.oup.com
Reverse vaccinology (RV) was described at its inception in 2000 as an in silico process that
starts from the genomic sequence of the pathogen and ends with a list of potential protein …

[HTML][HTML] Multi-epitope chimeric vaccine design against emerging Monkeypox virus via reverse vaccinology techniques- a bioinformatics and immunoinformatics …

S Aiman, Y Alhamhoom, F Ali, N Rahman… - Frontiers in …, 2022 - frontiersin.org
The emerging monkeypox virus (MPXV) is a zoonotic orthopoxvirus that causes infections in
humans similar to smallpox. Since May 2022, cases of monkeypox (MPX) have been …

Vaccinomics to Design a Multi-Epitopes Vaccine for Acinetobacter baumannii

M Ud-Din, A Albutti, A Ullah, S Ismail, S Ahmad… - International Journal of …, 2022 - mdpi.com
Antibiotic resistance (AR) is the result of microbes' natural evolution to withstand the action
of antibiotics used against them. AR is rising to a high level across the globe, and novel …

In silico design and analyses of a multi-epitope vaccine against Crimean-Congo hemorrhagic fever virus through reverse vaccinology and immunoinformatics …

AA Omoniyi, SS Adebisi, SA Musa, JO Nzalak… - Scientific Reports, 2022 - nature.com
Abstract Crimean Congo Hemorrhagic Fever virus (CCHFV) is a deadly human pathogen
that causes an emerging zoonotic disease with a broad geographic spread, especially in …

Multi-epitope vaccine design against monkeypox virus via reverse vaccinology method exploiting immunoinformatic and bioinformatic approaches

K Bhattacharya, IM Shamkh, MS Khan, MM Lotfy… - Vaccines, 2022 - mdpi.com
(1) Background: The monkeypox virus is a zoonotic orthopox DNA virus that is closely linked
to the virus. In light of the growing concern about this virus, the current research set out to …

Towards A Novel Multi-Epitopes Chimeric Vaccine for Simulating Strong Immune Responses and Protection against Morganella morganii

A Ullah, S Ahmad, S Ismail, Z Afsheen… - International Journal of …, 2021 - mdpi.com
Morganella morganii is one of the main etiological agents of hospital-acquired infections
and no licensed vaccine is available against the pathogen. Herein, we designed a multi …