Pemphigus is a group of IgG-mediated autoimmune diseases of stratified squamous
epithelia, such as the skin and oral mucosa, in which acantholysis (the loss of cell adhesion) …

Cadherins are a family of cell adhesion receptors that are crucial for the mutual association
of vertebrate cells. Through their homophilic binding interactions, cadherins play a role in …

Pemphigus vulgaris is a chronic autoimmune bullous dermatosis that results from the
production of autoantibodies against desmogleins 1 and 3. It is the most frequent and most …

Dermatology, edited by world authorities Jean L. Bolognia, MD, Joseph L. Jorizzo, MD, and
Julie V. Schaffer, MD, is an all-encompassing medical reference book that puts the latest …

Recently, we found that ZO-1, a tight junction-associated protein, was concentrated in the so
called isolated adherens junction fraction from the liver (Itoh, M., A. Nagafuchi, S. Yonemura …

The ability of carcinomas to invade and to metastasize largely depends on the degree of
epithelial differentiation within the tumors, ie, poorly differentiated being more invasive than …

Pemphigus vulgaris (PV) is a life-threatening skin disease in which autoantibodies against a
keratinocyte cell surface 130 kd glycoprotein, PV antigen (PVA), cause loss of cell-cell …

Pemphigus consists of a group of rare and severe autoimmune blistering diseases mediated
by pathogenic autoantibodies mainly directed against two desmosomal adhesion proteins …

Cadherins play an important role in specific cell-cell adhesion events. Their expression
appears to be tightly regulated during development and each tissue or cell type shows a …

Desmosomes are adhesive intercellular junctions that mechanically integrate adjacent cells
by coupling adhesive interactions mediated by desmosomal cadherins to the intermediate …