Clostridioides difficile: current overview and future perspectives
J Giles, A Roberts - Advances in Protein Chemistry and Structural Biology, 2022 - Elsevier
The most common world-wide cause of antibiotic-associated infectious diarrhea and colitis
is the toxin producing bacterium, Clostridioides difficile (C. difficile). Here we review the …
is the toxin producing bacterium, Clostridioides difficile (C. difficile). Here we review the …
The gut bacterial community potentiates Clostridioides difficile infection severity
The severity of Clostridioides difficile infections (CDI) has increased over the last few
decades. Patient age, white blood cell count, and creatinine levels as well as C. difficile …
decades. Patient age, white blood cell count, and creatinine levels as well as C. difficile …
Tauroursodeoxycholic acid inhibits Clostridioides difficile toxin-induced apoptosis
ABSTRACT C. difficile infection (CDI) is a highly inflammatory disease mediated by the
production of two large toxins that weaken the intestinal epithelium and cause extensive …
production of two large toxins that weaken the intestinal epithelium and cause extensive …
An osmotic laxative renders mice susceptible to prolonged Clostridioides difficile colonization and hinders clearance
Antibiotics are a major risk factor for Clostridioides difficile infections (CDIs) because of their
impact on the microbiota. However, nonantibiotic medications such as the ubiquitous …
impact on the microbiota. However, nonantibiotic medications such as the ubiquitous …
Diagnostic Guidance for C. difficile Infections
J van Prehn, MJT Crobach, A Baktash… - … on Clostridioides difficile …, 2024 - Springer
Diagnosis of Clostridioides difficile infection (CDI) can be challenging. First of all, there has
been debate on which of the two reference assays, cell cytotoxicity neutralization assay …
been debate on which of the two reference assays, cell cytotoxicity neutralization assay …