Angiogenesis forms new vessels from existing ones. Abnormal angiogenesis, which is what
gives tumor microenvironments their distinctive features, is characterised by convoluted …

Clustered regulatory interspaced short palindromic repeats (CRISPR) has changed
biomedical research and provided entirely new models to analyze every aspect of …

Epigenetics is the study of heritable changes in gene expression or function without altering
the DNA sequence. Important factors are part of epigenetic events, such as methylation …

Breast cancer is a global health challenge with staggering statistics underscoring its
pervasive impact. The burden of this disease is measured in terms of its prevalence and the …

Abstract Integrin β6 (ITGB6), a member of the integrin family of proteins, is only present in
epithelial tissues and frequently associates with integrin subunit αv to form transmembrane …

Cholangiocarcinoma is a rare tumor but a challenging cancer in terms of pathological
changes, clinical manifestations and therapeutic options. Recent studies have provided …

SIRT1 is a member of the sirtuin family functioning in the process of removal of acetyl groups
from different proteins. This protein has several biological functions and is involved in the …

RUNX2 and SOX9 are two pivotal transcriptional regulators of chondrogenesis. It has been
demonstrated that RUNX2 and SOX9 physically interact; RUNX2 transactivation may be …

miR-671 is encoded by a gene on 7q36. 1 and contributes to the pathogenesis of a variety of
disorders, including diverse types of cancers, atherosclerosis, ischemic stroke, liver fibrosis …

MicroRNAs (miRNAs) are crucial post-transcriptional regulators of gene expression, and
their deregulation contributes to many aspects of cancer development and progression …