The covalent nucleotide modifications within plant mRNAs: what we know, how we find them, and what should be done in the future
W Prall, DR Ganguly, BD Gregory - The Plant Cell, 2023 - academic.oup.com
Although covalent nucleotide modifications were first identified on the bases of transfer
RNAs (tRNAs) and ribosomal RNAs (rRNAs), a number of these epitranscriptome marks …
RNAs (tRNAs) and ribosomal RNAs (rRNAs), a number of these epitranscriptome marks …
Eukaryotic RNA 5′-end NAD+ capping and DeNADding
M Kiledjian - Trends in cell biology, 2018 - cell.com
A hallmark of eukaryotic mRNAs has long been the 5′-end m 7 G cap. This paradigm was
recently amended by recent reports that Saccharomyces cerevisiae and mammalian cells …
recently amended by recent reports that Saccharomyces cerevisiae and mammalian cells …
NAD+-capped RNAs are widespread in the Arabidopsis transcriptome and can probably be translated
As the most common RNA cap in eukaryotes, the 7-methylguanosine (m7G) cap impacts
nearly all processes that a messenger RNA undergoes, such as splicing, polyadenylation …
nearly all processes that a messenger RNA undergoes, such as splicing, polyadenylation …
Identification of NAD-RNA species and ADPR-RNA decapping in Archaea
JV Gomes-Filho, R Breuer, HG Morales-Filloy… - Nature …, 2023 - nature.com
NAD is a coenzyme central to metabolism that also serves as a 5′-terminal cap for bacterial
and eukaryotic transcripts. Thermal degradation of NAD can generate nicotinamide and …
and eukaryotic transcripts. Thermal degradation of NAD can generate nicotinamide and …
Xrn1 is a deNADding enzyme modulating mitochondrial NAD-capped RNA
The existence of non-canonical nicotinamide adenine diphosphate (NAD) 5′-end capped
RNAs is now well established. Nevertheless, the biological function of this nucleotide …
RNAs is now well established. Nevertheless, the biological function of this nucleotide …
Highly efficient 5' capping of mitochondrial RNA with NAD+ and NADH by yeast and human mitochondrial RNA polymerase
Bacterial and eukaryotic nuclear RNA polymerases (RNAPs) cap RNA with the oxidized and
reduced forms of the metabolic effector nicotinamide adenine dinucleotide, NAD+ and …
reduced forms of the metabolic effector nicotinamide adenine dinucleotide, NAD+ and …
Toll/interleukin-1 receptor (TIR) domain-containing proteins have NAD-RNA decapping activity
The occurrence of NAD+ as a non-canonical RNA cap has been demonstrated in diverse
organisms. TIR domain-containing proteins present in all kingdoms of life act in defense …
organisms. TIR domain-containing proteins present in all kingdoms of life act in defense …
Identification, biosynthesis, and decapping of NAD-capped RNAs in B. subtilis
J Frindert, Y Zhang, G Nübel, M Kahloon, L Kolmar… - Cell Reports, 2018 - cell.com
The ubiquitous coenzyme nicotinamide adenine dinucleotide (NAD) decorates various
RNAs in different organisms. In the proteobacterium Escherichia coli, the NAD-cap confers …
RNAs in different organisms. In the proteobacterium Escherichia coli, the NAD-cap confers …
NAD tagSeq reveals that NAD+-capped RNAs are mostly produced from a large number of protein-coding genes in Arabidopsis
The 5′ end of a eukaryotic mRNA transcript generally has a 7-methylguanosine (m7G) cap
that protects mRNA from degradation and mediates almost all other aspects of gene …
that protects mRNA from degradation and mediates almost all other aspects of gene …
ONE-seq: epitranscriptome and gene-specific profiling of NAD-capped RNA
K Niu, J Zhang, S Ge, D Li, K Sun, Y You… - Nucleic Acids …, 2023 - academic.oup.com
The hub metabolite, nicotinamide adenine dinucleotide (NAD), can be used as an initiating
nucleotide in RNA synthesis to result in NAD-capped RNAs (NAD-RNA). Since NAD has …
nucleotide in RNA synthesis to result in NAD-capped RNAs (NAD-RNA). Since NAD has …