Helminth infections and host immune regulation

HJ McSorley, RM Maizels - Clinical microbiology reviews, 2012 - Am Soc Microbiol
Helminth parasites infect almost one-third of the world's population, primarily in tropical
regions. However, regions where helminth parasites are endemic record much lower …

Regulation of immunity and allergy by helminth parasites

RM Maizels - Allergy, 2020 - Wiley Online Library
There is increasing interest in helminth parasite modulation of the immune system, both from
the fundamental perspective of the “arms race” between host and parasite, and equally …

Schistosomiasis in the People's Republic of China: the era of the Three Gorges Dam

DP McManus, DJ Gray, Y Li, Z Feng… - Clinical microbiology …, 2010 - Am Soc Microbiol
The potential impact of the Three Gorges Dam (TGD) on schistosomiasis transmission in
China has invoked considerable global concern. The TGD will result in changes in the water …

Chronic intestinal helminth infections are associated with immune hyporesponsiveness and induction of a regulatory network

CA Figueiredo, ML Barreto, LC Rodrigues… - Infection and …, 2010 - Am Soc Microbiol
Helminth infections have been associated with protection against allergy and autoimmune
diseases. We investigated the effects of chronic infections with Ascaris lumbricoides and …

Chronic helminth infections protect against allergic diseases by active regulatory processes

HH Smits, B Everts, FC Hartgers… - Current allergy and …, 2010 - Springer
Developed countries are suffering from an epidemic rise in immunologic disorders, such as
allergy-related diseases and certain autoimmunities. Several studies have demonstrated a …

Trichuris suis ova therapy for allergic rhinitis: a randomized, double-blind, placebo-controlled clinical trial

P Bager, J Arnved, S Rønborg, J Wohlfahrt… - Journal of allergy and …, 2010 - Elsevier
BACKGROUND: Parasitic helminth infections can protect against allergic airway
inflammation in experimental models and have been associated with a reduced risk of atopy …

Helminth infections decrease host susceptibility to immune-mediated diseases

JV Weinstock, DE Elliott - The Journal of Immunology, 2014 - journals.aai.org
Helminthic infection has become rare in highly industrialized nations. Concurrent with the
decline in helminthic infection has been an increase in the prevalence of inflammatory …

Strongyloides ratti infection induces expansion of Foxp3+ regulatory T cells that interfere with immune response and parasite clearance in BALB/c mice

B Blankenhaus, U Klemm, ML Eschbach… - The journal of …, 2011 - journals.aai.org
To escape expulsion by their host's immune system, pathogenic nematodes exploit
regulatory pathways that are intrinsic parts of the mammalian immune system, such as …

[HTML][HTML] The Schistosoma mansoni lipidome: Leads for immunomodulation

M Giera, MMM Kaisar, RJE Derks, E Steenvoorden… - Analytica Chimica …, 2018 - Elsevier
Schistosoma mansoni is a parasitic helminth that infects millions of people mostly in tropical
parts of the world. Different life cycle stages of S. mansoni, that infect or develop in the …

Trichinella spiralis‐secreted products modulate DC functionality and expand regulatory T cells in vitro

C Aranzamendi, F Fransen, M Langelaar… - Parasite …, 2012 - Wiley Online Library
Helminths and their products can suppress the host immune response which may benefit
parasite survival. Trichinella spiralis can establish chronic infections in a wide range of …