The pathobiology of vascular dementia

C Iadecola - Neuron, 2013 - cell.com
Vascular cognitive impairment defines alterations in cognition, ranging from subtle deficits to
full-blown dementia, attributable to cerebrovascular causes. Often coexisting with …

Past, present and future role of retinal imaging in neurodegenerative disease

AH Kashani, S Asanad, JW Chan, MB Singer… - Progress in retinal and …, 2021 - Elsevier
Retinal imaging technology is rapidly advancing and can provide ever-increasing amounts
of information about the structure, function and molecular composition of retinal tissue in …

From neurodevelopmental to neurodegenerative disorders: the vascular continuum

J Ouellette, B Lacoste - Frontiers in Aging Neuroscience, 2021 - frontiersin.org
Structural and functional integrity of the cerebral vasculature ensures proper brain
development and function, as well as healthy aging. The inability of the brain to store energy …

[HTML][HTML] A prospective open-label study of endovascular treatment of chronic cerebrospinal venous insufficiency

P Zamboni, R Galeotti, E Menegatti… - Journal of vascular …, 2009 - Elsevier
OBJECTIVE: Chronic cerebrospinal venous insufficiency (CCSVI) is characterized by
combined stenoses of the principal pathways of extracranial venous drainage, including the …

Vascular aspects of multiple sclerosis

M D'haeseleer, M Cambron, L Vanopdenbosch… - The Lancet …, 2011 - thelancet.com
Three types of vascular dysfunction have been described in multiple sclerosis (MS). First,
findings from epidemiological studies suggest that patients with MS have a higher risk for …

[HTML][HTML] How does neurovascular unit dysfunction contribute to multiple sclerosis?

JM Cashion, KM Young, BA Sutherland - Neurobiology of Disease, 2023 - Elsevier
Multiple sclerosis is an inflammatory demyelinating disease of the central nervous system
(CNS) and the most common non-traumatic cause of neurological disability in young adults …

Multiple sclerosis: the role of MR imaging

Y Ge - American Journal of Neuroradiology, 2006 - Am Soc Neuroradiology
MR offers by far the most sensitive technique for detecting multiple sclerosis (MS) lesions
and has proved to be an important paraclinical tool for diagnosing MS and monitoring …

Nonconventional MRI and microstructural cerebral changes in multiple sclerosis

C Enzinger, F Barkhof, O Ciccarelli, M Filippi… - Nature Reviews …, 2015 - nature.com
MRI has become the most important paraclinical tool for diagnosing and monitoring patients
with multiple sclerosis (MS). However, conventional MRI sequences are largely nonspecific …

Impaired cerebrovascular reactivity in multiple sclerosis

O Marshall, H Lu, JC Brisset, F Xu, P Liu… - JAMA …, 2014 - jamanetwork.com
Importance Cerebrovascular reactivity (CVR) is an inherent indicator of the dilatory capacity
of cerebral arterioles for a vasomotor stimulus for maintaining a spontaneous and instant …

Anomalous venous blood flow and iron deposition in multiple sclerosis

AV Singh, P Zamboni - Journal of Cerebral Blood Flow & …, 2009 - journals.sagepub.com
Multiple sclerosis (MS) is primarily an autoimmune disorder of unknown origin. This review
focuses iron overload and oxidative stress as surrounding cause that leads to …