The S100 proteins, a family of calcium-binding cytosolic proteins, have a broad range of
intracellular and extracellular functions through regulating calcium balance, cell apoptosis …

The S100 protein family consists of 24 members functionally distributed into three main
subgroups: those that only exert intracellular regulatory effects, those with intracellular and …

Abstract S100A8 and S100A9 are novel members of the group of damage–associated
molecular pattern molecules (DAMP) which are early amplifiers of innate immune responses …

The S100 family of EF-hand calcium (Ca 2+)-binding proteins is essential for a wide range of
cellular functions. During infection, certain S100 proteins act as damage-associated …

This review focuses on new aspects of extracellular roles of the calgranulins. S100A8,
S100A9 and S100A12 are constitutively expressed in neutrophils and induced in several …

Amplification of innate immune responses by endogenous danger‐associated molecular
patterns (DAMPs) promotes inflammation. The involvement of S100A8 and S100A9, DAMPs …

The S100 proteins comprise a family of 21 low molecular weight (9–13 kDa) proteins that
are characterized by the presence of two calcium-binding EF-hand motifs. Fourteen S100 …

The calgranulins are a subgroup of proteins in the S100 family (calgranulin A, S100A8;
calgranulin B, S100A9 and calgranulin C, S100A12) that provide protective anti-infective …

Atherogenesis is a complex process involving inflammation. S100A8 and S100A9, the Ca
2+-binding neutrophil cytosolic proteins, are associated with innate immunity and regulate …

Atherosclerosis is an arterial disease associated with dyslipidemia, abnormal arterial
calcification and oxidative stress. It has been shown that a continued chronic inflammatory …