Abstract Cullin-RING ligase 5 (CRL5) is a multi-protein complex and consists of a scaffold
protien cullin 5, a RING protein RBX2 (also known as ROC2 or SAG), adaptor proteins …

The ankyrin (ANK) SOCS box (ASB) family, encompassing ASB1–18, is the largest group of
substrate receptors of cullin 5 Ring E3 ubiquitin ligase. Nonetheless, the mechanism of …

Much remains to be discovered about the intersection of tissue-specific transcription control
and the epigenetics of skeletal muscle (SkM), a very complex and dynamic organ. From four …

Bovine digital dermatitis (BDD) is an infectious disease of the hoof in cattle with multifactorial
etiology and a polygenic influence on susceptibility. With our study, we identified genomic …

Variation in genes involved in the absorption, distribution, metabolism, and excretion of
drugs (ADME) can influence individual response to a therapeutic treatment. The study of …

Aim: Research suggests that Alzheimer's disease (AD) is heterogeneous with numerous
subtypes. Through a proprietary interactive ML system, several underlying biological …

Ankyrin repeat and SOCS box (ASB) family members have a C-terminal SOCS box and an N-
terminal ankyrin-related sequence of variable repeats. To date, the roles of ASB family …

Abstract Background Neuromuscular junctions (NMJs) are chemical synapses formed
between motor neurons and skeletal muscle fibers and are essential for controlling muscle …

Ένα από τα πιο εντυπωσιακά χαρακτηριστικά του Νευρικού Συστήματος των σπονδυλωτών
είναι η ποικιλομορφία των κυτταρικών τύπων που το αποτελούν. Η κατανόηση της …

La sénescence est un processus caractérisé par un arrêt stable du cycle cellulaire. Ce
mécanisme peut être induit en réponse à de nombreux stress, comme l'activation d'un …