Microbial infections are controlled by host inflammatory responses that are initiated by
innate immune receptors after recognition of conserved microbial products. As inflammation …

Salmonella infection causes morbidity and mortality throughout the world with the host
immune response varying depending on whether the infection is acute and limited, or …

Typhoid fever is estimated to have caused 21· 6 million illnesses and 216 500 deaths
globally in 2000, affecting all ages. There is also one case of paratyphoid fever for every four …

Persistent bacterial infections involving Mycobacterium tuberculosis, Salmonella enterica
serovar Typhi (S. typhi) and Helicobacter pylori pose significant public-health problems …

Host-adapted strains of Salmonella are capable of establishing a persistent infection in their
host often in the absence of clinical disease. The mouse model of Salmonella infection has …

MICROBIOLOGY AND NOMENCLATURE The organisms that belong to the genus
Salmonella are motile, gram-negative, facultative anaerobic bacilli and are classified within …

Host-adapted Salmonella strains are responsible for a number of disease manifestations in
mammals, including an asymptomatic chronic infection in which bacteria survive within …

Salmonella enterica serovar Typhi (S. Typhi), the aetiologic agent of typhoid fever, is a
human restricted pathogen. The molecular mechanism of Salmonella pathogenicity is …

Salmonella enterica serovars Typhi and Paratyphi are the causative agents of human
typhoid fever. Current typhoid vaccines are ineffective and are not widely used in endemic …

Salmonella enterica serovar Typhi (S. Typhi) causes typhoid fever, a life-threatening human
disease. The lack of animal models due to S. Typhi's strict human host specificity has …