[HTML][HTML] Translating RNA sequencing into clinical diagnostics: opportunities and challenges

SA Byron, KR Van Keuren-Jensen… - Nature Reviews …, 2016 - nature.com
With the emergence of RNA sequencing (RNA-seq) technologies, RNA-based biomolecules
hold expanded promise for their diagnostic, prognostic and therapeutic applicability in …

MicroRNAs in development and disease

D Sayed, M Abdellatif - Physiological reviews, 2011 - journals.physiology.org
MicroRNAs (miRNAs) are a class of posttranscriptional regulators that have recently
introduced an additional level of intricacy to our understanding of gene regulation. There are …

The role of Epstein–Barr virus in epithelial malignancies

SW Tsao, CM Tsang, KF To, KW Lo - The Journal of pathology, 2015 - Wiley Online Library
The close association of Epstein–Barr virus (EBV) infection with non‐keratinizing
nasopharyngeal carcinomas and a subset of gastric carcinomas suggests that EBV infection …

Update on Epstein-Barr virus and gastric cancer

A Shinozaki-Ushiku, A Kunita… - … journal of oncology, 2015 - spandidos-publications.com
Epstein-Barr virus-associated gastric carcinoma (EBVaGC) is a distinct subtype that
accounts for nearly 10% of gastric carcinomas. EBVaGC is defined by monoclonal …

[HTML][HTML] Virus-encoded microRNAs

A Grundhoff, CS Sullivan - Virology, 2011 - Elsevier
MicroRNAs (miRNAs) are the subject of enormous interest. They are small non-coding
RNAs that play a regulatory role in numerous and diverse cellular processes such as …

[HTML][HTML] Translational genomics of nasopharyngeal cancer

CM Tsang, VWY Lui, JP Bruce, TJ Pugh… - Seminars in cancer biology, 2020 - Elsevier
Nasopharyngeal carcinoma (NPC), also named the Cantonese cancer, is a unique cancer
with strong etiological association with infection of the Epstein-Barr virus (EBV). With …

The viral and cellular microRNA targetome in lymphoblastoid cell lines

RL Skalsky, DL Corcoran, E Gottwein, CL Frank… - PLoS …, 2012 - journals.plos.org
Epstein-Barr virus (EBV) is a ubiquitous human herpesvirus linked to a number of B cell
cancers and lymphoproliferative disorders. During latent infection, EBV expresses 25 viral …

Epstein–Barr virus-encoded microRNA BART1 induces tumour metastasis by regulating PTEN-dependent pathways in nasopharyngeal carcinoma

L Cai, Y Ye, Q Jiang, Y Chen, X Lyu, J Li… - Nature …, 2015 - nature.com
Abstract Epstein–Barr virus (EBV), aetiologically linked to nasopharyngeal carcinoma
(NPC), is the first human virus found to encode many miRNAs. However, how these viral …

Viral microRNA targetome of KSHV-infected primary effusion lymphoma cell lines

E Gottwein, DL Corcoran, N Mukherjee, RL Skalsky… - Cell host & …, 2011 - cell.com
Primary effusion lymphoma (PEL) is caused by Kaposi's sarcoma-associated herpesvirus
(KSHV) and frequently also harbors Epstein-Barr virus (EBV). The expression of KSHV-and …

EBV and human microRNAs co‐target oncogenic and apoptotic viral and human genes during latency

KJ Riley, GS Rabinowitz, TA Yario, JM Luna… - The EMBO …, 2012 - embopress.org
Epstein–Barr virus (EBV) controls gene expression to transform human B cells and maintain
viral latency. High‐throughput sequencing and crosslinking immunoprecipitation (HITS …