Antiviral activities of antibodies may either be dependent only on interactions between the
antibody and cognate antigen, as in binding and neutralization of an infectious virion, or …

Monoclonal antibodies (mAbs) are increasingly being considered as agents to fight severe
viral diseases. So far, they have essentially been selected and used on the basis of their …

Epstein–Barr virus (EBV) infects 95% of the adult population and is the cause of infectious
mononucleosis. It is also associated with 1% of cancers worldwide, such as nasopharyngeal …

The immune system is comprised of two principal interconnected components called innate
and adaptive immunity. While the innate immune system mounts a nonspecific response that …

Allorecognition is the activation of the adaptive immune system to foreign human leukocyte
antigen (HLA) resulting in the generation of alloantibodies. Due to a high polymorphism …

Both targeted and genome-wide studies have revealed genetic associations for
susceptibility, prognosis, and treatment-induced secondary malignancies and toxicities in …

Fc receptors play a central role in maintaining the homeostatic balance in the immune
system. Our knowledge of the structure and function of these receptors and their naturally …

Analyses of human clinical HIV-1 vaccine trials and preclinical vaccine studies performed in
rhesus macaque (RM) models have identified associations between non-neutralizing Fc …

Objective IgG Fc receptors (FcγRs) play important roles in immune responses. It is not clear
whether FcγR receptors play a role in human asthma and allergy. The aim of current study …

In the current era, one of the major factors limiting graft survival is chronic antibody-mediated
rejection (ABMR), whilst patient survival is impacted by the effects of immunosuppression on …