Over the last decade, adipose‐derived stem cells (ADSCs) have attracted increasing
attention in the field of regenerative medicine. ADSCs appear to be the most advantageous …

Sphincter dysfunction often occurs at the end of tubule organs such as the urethra, anus, or
gastroesophageal sphincters. It is the primary consequence of neuromuscular impairment …

Photobiomodulation (PBM), the use of biocompatible tissue-penetrating light to interact with
intracellular chromophores to modulate the fates of cells and tissues, has emerged as a …

Different types of lasers have been applied for various proctological conditions. We discuss
about published articles regarding the application of lasers, with concern about evidence …

Anal sphincter incontinence is a chronic disease, which dramatically impairs quality of life
and induces high costs for the society. Surgery, considered as the best curative option …

Background The efficacy of cell implantation via 3D-spheroids to treat basal tone in fecal
incontinence remains unclear. To address this, in this study, we aimed to identify cell …

Tumor progression depends on the collaborative interactions between tumor cells and the
surrounding stroma. First-line therapies direct against cancer cells may not reach a …

The complexity in the molecular mechanism of the internal anal sphincter (IAS) limits
preclinical or clinical outcomes of fecal incontinence (FI) treatment. So far, there are no …

Introduction Fecal incontinence (FI) is caused by external anal sphincter injury. Vitamin E is
a potential strategy for anal sphincter muscle repair via its antioxidant, anti-inflammatory, anti …

Aim The aim of this study was to investigate whether the application of nanofat containing
stem cells improves continence in women who had previously undergone anal …