[HTML][HTML] Role of Nigella sativa and Its Constituent Thymoquinone on Chemotherapy-Induced Nephrotoxicity: Evidences from Experimental Animal Studies

M Cascella, G Palma, A Barbieri, S Bimonte… - Nutrients, 2017 - mdpi.com
Background: Most chemotherapeutic drugs are known to cause nephrotoxicity. Therefore,
new strategies have been considered to prevent chemotherapy-induced nephrotoxicity. It is …

Advances in combination therapy of lung cancer: Rationales, delivery technologies and dosage regimens

L Wu, D Leng, D Cun, C Foged, M Yang - Journal of Controlled Release, 2017 - Elsevier
Lung cancer is a complex disease caused by a multitude of genetic and environmental
factors. The progression of lung cancer involves dynamic changes in the genome and a …

[HTML][HTML] Renoprotective effects of stevia (Stevia rebaudiana Bertoni), amlodipine, valsartan, and losartan in gentamycin-induced nephrotoxicity in the rat model …

F Rizwan, S Yesmine, SG Banu, IA Chowdhury… - Toxicology reports, 2019 - Elsevier
The current study investigated the renoprotective effects of stevia, angiotensin-II type 1
receptor (AT 1) blocker and calcium (Ca 2+) channel blocker in gentamycin-induced …

Comparison of the ameliorative roles of crab chitosan nanoparticles and mesenchymal stem cells against cisplatin-triggered nephrotoxicity

AA Shati, J Alkabli, MY Alfaifi, SEI Elbehairi… - International Journal of …, 2023 - Elsevier
Aim In the present investigation, we compared the effects of mesenchymal stem cells
extracted from bone marrow (BMSCs) and crab chitosan nanoparticles (CCNPs) on renal …

Synergistic protective role of ceftriaxone and ascorbic acid against subacute diazinon-induced nephrotoxicity in rats

MM Abdel-Daim - Cytotechnology, 2016 - Springer
Diazinon (DZN) is a synthetic organophosphrus acaricide and insecticide widely used for
veterinary and agricultural purposes. However, its animal and human exposure leads to …

The effect of N-acetylcysteine on inflammation and oxidative stress in cisplatin-induced nephrotoxicity: a rat model

İ Güntürk, C Yazici, SK Köse, F Dağli… - Turkish Journal of …, 2019 - journals.tubitak.gov.tr
Background/Aim: Cisplatin is a highly effective chemotherapeutic agent used in the
treatment of solid organ cancers. Besides its chemotherapeutic effectiveness, cisplatin …

[HTML][HTML] Cisplatin-induced nephrotoxicity; protective supplements and gender differences

M Nematbakhsh, Z Pezeshki, FE Jazi… - Asian Pacific journal …, 2017 - ncbi.nlm.nih.gov
Cisplatin (CDDP) has been widely used as a chemotherapeutic agent for solid tumors. The
most common side effect of CDDP is nephrotoxicity, and many efforts have been made in the …

Vitamin E, Vitamin C, or Losartan Is Not Nephroprotectant against Cisplatin‐Induced Nephrotoxicity in Presence of Estrogen in Ovariectomized Rat Model

M Nematbakhsh, Z Pezeshki… - International journal …, 2012 - Wiley Online Library
Background. The nephroprotective effect of vitamins E and C or losartan against cisplatin
(CP)‐induced nephrotoxicity when they are accompanied by estrogen was investigated …

Renoprotective effects of angiotensin receptor blocker and stem cells in acute kidney injury: involvement of inflammatory and apoptotic markers

IO Sherif, LA Al-Mutabagani… - Experimental …, 2015 - journals.sagepub.com
Cisplatin, Cis-diamminedichloroplatinum (CDDP), is a platinum-based chemotherapy drug,
and its chemotherapeutic use is restricted by nephrotoxicity. Inflammatory and apoptotic …

Amelioration of cisplatin-induced nephrotoxicity in rats by triterpenoid saponin of Terminalia arjuna

IO Sherif - Clinical and experimental nephrology, 2015 - Springer
Background Cisplatin is a potent anti-tumor compound. Nephrotoxicity-inducing oxidative
stress is a common side effect. This study was conducted to find out whether, the triterpenoid …