Anillin is a highly conserved multidomain protein that interacts with cytoskeletal components
as well as their regulators. Throughout phylogeny, Anillins contribute to cytokinesis, the cell …

Stable intercellular bridges are a conserved feature of gametogenesis in multicellular
animals observed more than 100 years ago, but their function was unknown. Many of the …

During embryogenesis tissue layers undergo morphogenetic flow rearranging and folding
into specific shapes. While developmental biology has identified key genes and local …

We report the cDNA sequence and localization of a protein first identified by actin filament
chromatography of Drosophila embryo extracts as ABP8 (Miller, KG, CM Field, and BM …

Polarized cells contain numerous membrane domains, but it is unclear how the formation of
these domains is coordinated to create a single integrated cell architecture. Genetic screens …

Cellularization of the Drosophila embryo results in the formation of a cell monolayer with
many characteristics of a polarized epithelium. We have used antibodies specific to cellular …

Transposon control is a critical process during reproduction. The PIWI family proteins can
play a key role, using a piRNA-mediated slicing mechanism to suppress transposon activity …

Adhesion molecules of the cadherin superfamily have an important role during vertebrate
development. The DE-cadherin homolog DE-cadherin is the first classic cadherin isolated …

ABSTRACT wingless/wnt-1 signaling directs cell fate during development. Genetic analysis
in Drosophila identified genes that may encode components of the wingless signal …

The early Drosophila embryo undergoes two distinct membrane invagination events
believed to be mechanistically related to cytokinesis: metaphase furrow formation and …