Mechanistic insight into oxidative stress-triggered signaling pathways and type 2 diabetes

A Singh, R Kukreti, L Saso, S Kukreti - Molecules, 2022 - mdpi.com
Oxidative stress (OS) is a metabolic dysfunction mediated by the imbalance between the
biochemical processes leading to elevated production of reactive oxygen species (ROS) …

[HTML][HTML] Type 2 diabetes mellitus, oxidative stress and inflammation: examining the links

OO Oguntibeju - International journal of physiology …, 2019 - ncbi.nlm.nih.gov
Diabetes mellitus has been recognised as one of the four major non-communicable
diseases that demands urgent attention from all key shareholders globally in an effort to …

Assessment of lipid peroxidation by measuring malondialdehyde (MDA) and relatives in biological samples: Analytical and biological challenges

D Tsikas - Analytical biochemistry, 2017 - Elsevier
Abstract Malondialdehyde (MDA), 4-hydroxy-nonenal (HNE) and the F 2-isoprostane 15 (S)-
8-iso-prostaglandin F 2α (15 (S)-8-iso-PGF 2α) are the best investigated products of lipid …

Molecular mechanism of diabetic neuropathy and its pharmacotherapeutic targets

S Dewanjee, S Das, AK Das, N Bhattacharjee… - European journal of …, 2018 - Elsevier
Diabetic neuropathy is regarded as one of the most debilitating outcomes of diabetes
mellitus and may cause pain, decreased motility, and even amputation. Diabetic neuropathy …

Oxidative toxicity in diabetes and Alzheimer's disease: mechanisms behind ROS/RNS generation

W Ahmad, B Ijaz, K Shabbiri, F Ahmed… - Journal of biomedical …, 2017 - Springer
Reactive oxidative species (ROS) toxicity remains an undisputed cause and link between
Alzheimer's disease (AD) and Type-2 Diabetes Mellitus (T2DM). Patients with both AD and …

Diabetes, oxidative stress and therapeutic strategies

L Rochette, M Zeller, Y Cottin, C Vergely - Biochimica et Biophysica Acta …, 2014 - Elsevier
Background Diabetes has emerged as a major threat to health worldwide. Scope of Review
The exact mechanisms underlying the disease are unknown; however, there is growing …

Oxidative stress and the etiology of insulin resistance and type 2 diabetes

EJ Henriksen, MK Diamond-Stanic… - Free Radical Biology and …, 2011 - Elsevier
The condition of oxidative stress arises when oxidant production exceeds antioxidant activity
in cells and plasma. The overabundance of oxidants is mechanistically connected to the …

The biological role of vitamins in athletes' muscle, heart and microbiota

M Brancaccio, C Mennitti, A Cesaro, F Fimiani… - International journal of …, 2022 - mdpi.com
Physical activity, combined with adequate nutrition, is considered a protective factor against
cardiovascular disease, musculoskeletal disorders, and intestinal dysbiosis. Achieving …

Prolonged fasting times reap greater geroprotective effects when combined with caloric restriction in adult female mice

E Duregon, ME Fernandez, JM Romero… - Cell metabolism, 2023 - cell.com
Emerging new evidence highlights the importance of prolonged daily fasting periods for the
health and survival benefits of calorie restriction (CR) and time-restricted feeding (TRF) in …

Oxidative stress and lipid peroxidation: prospective associations between ferroptosis and delayed wound healing in diabetic ulcers

J Feng, J Wang, Y Wang, X Huang, T Shao… - Frontiers in cell and …, 2022 - frontiersin.org
Diabetic ulcers are one of the major complications of diabetes, and patients usually suffer
from amputation and death due to delayed ulcer wound healing. Persistent inflammation …