Foot-and-mouth disease vaccines: recent updates and future perspectives

M Kamel, A El-Sayed, H Castañeda Vazquez - Archives of virology, 2019 - Springer
Foot-and-mouth disease (FMD) is a major worldwide viral disease in animals, affecting the
national and international trade of livestock and animal products and leading to high …

The need for improved vaccines against foot-and-mouth disease

T De Los Santos, F Diaz-San Segundo… - Current opinion in …, 2018 - Elsevier
Highlights•Foot-and-mouth disease (FMD) is a serious threat to animal agriculture
worldwide.•Despite vaccine availability for over 70 years, FMD remains endemic …

Use of virus-like particles and nanoparticle-based vaccines for combating picornavirus infections

M Ren, SW Abdullah, C Pei, H Guo, S Sun - Veterinary Research, 2024 - Springer
Picornaviridae are non-enveloped ssRNA viruses that cause diseases such as poliomyelitis,
hand-foot-and-mouth disease (HFMD), hepatitis A, encephalitis, myocarditis, and foot-and …

Peptide dendrimers as valuable biomaterials in medical sciences

FST Mirakabad, MS Khoramgah, K Keshavarz… - Life sciences, 2019 - Elsevier
Peptides are oligomers of amino acids, which have been used in a wide range of
applications, particularly in medical and pharmaceutical sciences. Linear peptides have …

Peptide-based vaccines: foot-and-mouth disease virus, a paradigm in animal health

M Forner, R Cañas-Arranz, S Defaus, P de León… - Vaccines, 2021 - mdpi.com
Vaccines are considered one of the greatest global health achievements, improving the
welfare of society by saving lives and substantially reducing the burden of infectious …

Advanced foot-and-mouth disease vaccine platform for stimulation of simultaneous cellular and humoral immune responses

MJ Lee, H Jo, SH Park, MK Ko, SM Kim, B Kim, JH Park - Vaccines, 2020 - mdpi.com
Currently available commercial foot-and-mouth disease (FMD) vaccines have various
limitations, such as the slow induction and short-term maintenance of antibody titers …

A Single Dose of Dendrimer B2T Peptide Vaccine Partially Protects Pigs against Foot-and-Mouth Disease Virus Infection

R Cañas-Arranz, M Forner, S Defaus, P de León… - Vaccines, 2020 - mdpi.com
Foot-and-mouth disease virus (FMDV) causes a highly contagious disease of cloven-hoofed
animals whose control relies on efficient vaccination. We have reported that dendrimer …

[HTML][HTML] Virulence and Immune Evasion Strategies of FMDV: Implications for Vaccine Design

GN Medina, F Diaz San Segundo - Vaccines, 2024 - mdpi.com
Foot-and-mouth disease (FMD) is globally recognized as a highly economically devastating
and prioritized viral disease affecting livestock. Vaccination remains a crucial preventive …

Immunogenicity of a Dendrimer B2T Peptide Harboring a T-Cell Epitope From FMDV Non-structural Protein 3D

R Cañas-Arranz, P de León, M Forner… - Frontiers in Veterinary …, 2020 - frontiersin.org
Synthetic dendrimer peptides are a promising strategy to develop new FMD vaccines. A
dendrimer peptide, termed B2T-3A, which harbors two copies of the major FMDV antigenic B …

FMD empty capsids combined with the Immunostant Particle Adjuvant-ISPA or ISA206 induce protective immunity against foot and mouth disease virus

J Bidart, A Mignaqui, C Kornuta, G Lupi, M Gammella… - Virus Research, 2021 - Elsevier
Abstract Foot and Mouth Disease Virus (FMDV) causes economy losses and is controlled by
vaccination in many countries. Vaccine formulations based on empty capsids or Virus-Like …