Mitotic spindle assembly in animal cells: a fine balancing act
SL Prosser, L Pelletier - Nature Reviews Molecular Cell Biology, 2017 - nature.com
The mitotic spindle has a crucial role in ensuring the accurate segregation of chromosomes
into the two daughter cells during cell division, which is paramount for maintaining genome …
into the two daughter cells during cell division, which is paramount for maintaining genome …
Mechanobiology and developmental control
T Mammoto, A Mammoto… - Annual review of cell and …, 2013 - annualreviews.org
Morphogenesis is the remarkable process by which cells self-assemble into complex tissues
and organs that exhibit specialized form and function during embryological development …
and organs that exhibit specialized form and function during embryological development …
[HTML][HTML] Mitotic spindle orientation in asymmetric and symmetric cell divisions during animal development
X Morin, Y Bellaïche - Developmental cell, 2011 - cell.com
The orientation of the mitotic spindle has been proposed to control cell fate choices, tissue
architecture, and tissue morphogenesis. Here, we review the mechanisms regulating the …
architecture, and tissue morphogenesis. Here, we review the mechanisms regulating the …
Intracellular softening and increased viscoelastic fluidity during division
S Hurst, BE Vos, M Brandt, T Betz - Nature Physics, 2021 - nature.com
The life and death of an organism rely on correct cell division, which occurs through the
process of mitosis. Although the biochemical signalling and morphogenetic processes …
process of mitosis. Although the biochemical signalling and morphogenetic processes …
Emerging mechanisms of asymmetric stem cell division
ZG Venkei, YM Yamashita - Journal of Cell Biology, 2018 - rupress.org
The asymmetric cell division of stem cells, which produces one stem cell and one
differentiating cell, has emerged as a mechanism to balance stem cell self-renewal and …
differentiating cell, has emerged as a mechanism to balance stem cell self-renewal and …
Chromosome-and spindle-pole-derived signals generate an intrinsic code for spindle position and orientation
T Kiyomitsu, IM Cheeseman - Nature cell biology, 2012 - nature.com
Mitotic spindle positioning by cortical pulling forces defines the cell division axis and
location, which is critical for proper cell division and development. Although recent work has …
location, which is critical for proper cell division and development. Although recent work has …
Anisotropy of cell adhesive microenvironment governs cell internal organization and orientation of polarity
Control of the establishment of cell polarity is an essential function in tissue morphogenesis
and renewal that depends on spatial cues provided by the extracellular environment. The …
and renewal that depends on spatial cues provided by the extracellular environment. The …
Influence of cell geometry on division-plane positioning
The spatial organization of cells depends on their ability to sense their own shape and size.
Here, we investigate how cell shape affects the positioning of the nucleus, spindle and …
Here, we investigate how cell shape affects the positioning of the nucleus, spindle and …
What determines cell size?
© 2012 Marshall et al; licensee BioMed Central Ltd. This is an Open Access article
distributed under the terms of the Creative Commons Attribution License (http …
distributed under the terms of the Creative Commons Attribution License (http …
Cytoskeletal control of early mammalian development
The cytoskeleton—comprising actin filaments, microtubules and intermediate filaments—
serves instructive roles in regulating cell function and behaviour during development …
serves instructive roles in regulating cell function and behaviour during development …