Reactive oxygen species (ROS) play a critical role in defining the functional competence of
human spermatozoa. When generated in moderate amounts, ROS promote sperm …

The comprehensive anabolic effects of insulin throughout the body, in addition to the control
of glycemia, include ensuring lipid homeostasis and anti-inflammatory modulation …

An overview of the sperm metabolism is presented; using the stallion as a model we review
glycolysis, Krebs Cycle and oxidative phosphorylation, paying special attention to the …

Spermatogonial stem cells exhibit a low level of spontaneous mutation that is heavily
impacted by paternal age via mechanisms that appear to involve the aberrant repair of DNA …

The rising incidence of obesity has coincided with rising levels of poor reproductive
outcomes. The molecular basis for the association of infertility in obese males is now being …

Abstracts Ethnopharmacological relevance A traditional Chinese medicine experience
compound known as Yipibushen (YPBS) decoction stimulates qi and nourishes yin …

Diets leading to caloric overload are linked to metabolic disorders and reproductive function
impairment. Metabolic and hormonal abnormalities stand out as defining features of …

Significance: Proper functionality of the spermatozoa depends on the tight regulation of their
redox status; at the same time these cells are highly energy demanding and in the energetic …

Boar fertility is a key determinant of the production efficiency of the whole pig breeding
industry and boar sperm motility is the seminal parameter with the greatest impact on the …

STUDY QUESTION Can a high-throughput screening (HTS) platform facilitate male fertility
drug discovery? SUMMARY ANSWER An HTS platform identified a large number of …