Dysfunction of the immune system can result in damage of the peripheral nervous system.
The immunological mechanisms, which include macrophage infiltration, inflammation and …

To revise the 2010 consensus guideline on chronic inflammatory demyelinating
polyradiculoneuropathy (CIDP). Seventeen disease experts, a patient representative, and …

Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) consists of a spectrum
of autoimmune diseases of the peripheral nerves, causing weakness and sensory …

Abstract The nodes of Ranvier (NoR) are essential domains for nerve conduction and their
disruption plays a key role in the pathophysiology of immune‐mediated neuropathies. Our …

The discovery of autoantibodies against nodal and paranodal proteins has proven useful in
clinical practice, has uncovered novel pathophysiological mechanisms, clinical phenotypes …

Assays for anti-MAG antibodies by Enzyme-Linked Immunosorbent Assay can be improved
by testing for antibody binding at multiple serum dilutions, the inclusion of antigen-negative …

Abstract Diagnosing Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) poses
numerous challenges. The heterogeneous presentations of CIDP variants, its mimics, and …

Autoimmune neuropathies are a heterogeneous group of rare and disabling diseases in
which the immune system targets peripheral nervous system antigens and that respond to …

Background: Up to 20% of patients with chronic immune-mediated sensorimotor
neuropathies (CIN) do not respond adequately to first-line therapies. However, studies on …

Over the past 30 years, about 20 antibodies have been identified in immune-mediated
neuropathies, recognizing membrane or intracellular proteins or glycolipids of neuron and …