The conserved omega (ω) subunit of RNA polymerase (RNAP) is the only nonessential
subunit of bacterial RNAP core. The small ω subunit (7 kDa–11.5 kDa) contains three …

Programmable gene activation enables fine‐tuned regulation of endogenous and synthetic
gene circuits to control cellular behavior. While CRISPR‐Cas‐mediated gene activation has …

Governance of the endogenous gene regulatory network enables the navigation of cells
towards beneficial traits for recombinant protein production. CRISPRactivation and …

Staphylococcus aureus generates biofilms during many chronic human infections, which
contributes to its growth and persistence in the host. Multiple genes and pathways …

Gene transfer agents (GTAs) are small virus-like particles that indiscriminately package and
transfer any DNA present in their host cell, with clear implications for bacterial evolution. The …

Background It is important to explore the interaction between antibacterial nanoparticles and
microbes for understanding bactericidal activity and developing novel applications. It is …

Numerous factors have, to date, been identified as playing a role in the regulation of Agr
activity in Staphylococcus aureus, including transcription factors, antisense RNAs, and host …

Anti-microbial resistant infection is predicted to be alarming in upcoming years. In the
present study, we proposed co-localization of two model drugs viz., rifampicin and …

Introduction Pseudomonas fluorescens 2P24 was isolated from soil of natural decay
associated with wheat take-all and it can effectively control soil-borne diseases caused by a …

Small bacteriophage-like particles called gene transfer agents (GTAs) that mediate DNA
transfer between cells are produced by a variety of prokaryotes. The model GTA, produced …