Seizure‐induced oxidative stress in temporal lobe epilepsy

S Puttachary, S Sharma, S Stark… - BioMed research …, 2015 - Wiley Online Library
An insult to the brain (such as the first seizure) causes excitotoxicity, neuroinflammation, and
production of reactive oxygen/nitrogen species (ROS/RNS). ROS and RNS produced during …

Oxidative stress in epilepsy

U Geronzi, F Lotti, S Grosso - Expert Review of Neurotherapeutics, 2018 - Taylor & Francis
Introduction: The brain is particularly susceptible to oxidative stress being the most
aerobically active organ in the body due to its high metabolic demands. There is evidence …

Effect of probiotic supplementation on seizure activity and cognitive performance in PTZ-induced chemical kindling

S Bagheri, A Heydari, A Alinaghipour, M Salami - Epilepsy & Behavior, 2019 - Elsevier
Epilepsy is one of the most common neurological disorders that severely affect life quality of
many people worldwide. Ion transport in the neuronal membrane, inhibitory–excitatory …

Inflammation and reactive oxygen species in status epilepticus: Biomarkers and implications for therapy

G Terrone, F Frigerio, S Balosso, T Ravizza… - Epilepsy & Behavior, 2019 - Elsevier
Preclinical studies in immature and adult rodents and clinical observations show that
neuroinflammation and oxidative stress are rapid onset phenomena occurring in the brain …

Approaches for reactive oxygen species and oxidative stress quantification in epilepsy

R Olowe, S Sandouka, A Saadi, T Shekh-Ahmad - Antioxidants, 2020 - mdpi.com
Oxidative stress (OS) and excessive reactive oxygen species (ROS) production have been
implicated in many neurological pathologies, including acute seizures and epilepsy. Seizure …

Autism and dietary therapy: case report and review of the literature

MR Herbert, JA Buckley - Journal of child neurology, 2013 - journals.sagepub.com
We report the history of a child with autism and epilepsy who, after limited response to other
interventions following her regression into autism, was placed on a gluten-free, casein-free …

Antioxidants as a preventive treatment for epileptic process: a review of the current status

B Martinc, I Grabnar, T Vovk - Current neuropharmacology, 2014 - ingentaconnect.com
Epilepsy is known as one of the most frequent neurological diseases, characterized by an
enduring predisposition to generate epileptic seizures. Oxidative stress is believed to …

Targeting ferroptosis: A novel therapeutic strategy for the treatment of mitochondrial disease-related epilepsy

AH Kahn-Kirby, A Amagata, CI Maeder, JJ Mei… - PLoS …, 2019 - journals.plos.org
Background Mitochondrial disease is a family of genetic disorders characterized by defects
in the generation and regulation of energy. Epilepsy is a common symptom of mitochondrial …

[HTML][HTML] Interweaving epilepsy and neurodegeneration: Vitamin E as a treatment approach

AB Upaganlawar, NL Wankhede, MB Kale… - Biomedicine & …, 2021 - Elsevier
Epilepsy is the most common neurological disorder, affecting nearly 50 million people
worldwide. The condition can be manifested either due to genetic predisposition or acquired …

Reactive oxygen species mediate cognitive deficits in experimental temporal lobe epilepsy

JN Pearson, S Rowley, LP Liang, AM White… - Neurobiology of …, 2015 - Elsevier
Cognitive dysfunction is an important comorbidity of temporal lobe epilepsy (TLE). However,
no targeted therapies are available and the mechanisms underlying cognitive impairment …