Diagnosis and treatment of type 1 diabetes at the dawn of the personalized medicine era

AAS Akil, E Yassin, A Al-Maraghi, E Aliyev… - Journal of translational …, 2021 - Springer
Type 1 diabetes affects millions of people globally and requires careful management to
avoid serious long-term complications, including heart and kidney disease, stroke, and loss …

Therapeutic potential of mesenchymal stem cells for diabetes

A Moreira, S Kahlenberg… - Journal of molecular …, 2017 - jme.bioscientifica.com
Mesenchymal stem cells (MSCs) are self-renewing multipotent cells that have the capacity to
secrete multiple biologic factors that can restore and repair injured tissues. Preclinical and …

Wharton's jelly mesenchymal stem cells: a concise review of their secretome and prospective clinical applications

H Drobiova, S Sindhu, R Ahmad, D Haddad… - Frontiers in Cell and …, 2023 - frontiersin.org
Accumulating evidence indicates that most primary Wharton's jelly mesenchymal stem cells
(WJ-MSCs) therapeutic potential is due to their paracrine activity, ie, their ability to modulate …

Sources and therapeutic strategies of mesenchymal stem cells in regenerative medicine

M Kamal, D Kassem, KH Haider - Handbook of stem cell therapy, 2022 - Springer
During the past decade, mesenchymal stem cells (MSCs) have made their mark as a
potential weapon in regenerative medicine. Since their first isolation by Friedenstein in the …

Therapeutic efficacy of umbilical cord-derived stem cells for diabetes mellitus: a meta-analysis study

DH Kassem, MM Kamal - Stem Cell Research & Therapy, 2020 - Springer
Background Stem cell therapy provides great hope for patients with diabetes mellitus (DM).
DM is a seriously alarming metabolic disease characterized by hyperglycemia and β cell …

Therapeutic potential of Wharton's jelly mesenchymal stem cells for diabetes: achievements and challenges

MM Kamal, DH Kassem - Frontiers in cell and developmental biology, 2020 - frontiersin.org
Diabetes mellitus (DM) is an alarming metabolic disease in which insulin secreting β-cells
are damaged to various extent. Unfortunately, although currently available treatments help …

The other side of progestins: effects in the brain

S Giatti, RC Melcangi… - Journal of Molecular …, 2016 - jme.bioscientifica.com
Progestins are a broad class of progestational agents widely differing in their chemical
structures and pharmacological properties. Despite emerging data suggest that progestins …

Mesenchymal stem cell-based therapy for diabetes mellitus: enhancement strategies and future perspectives

H Li, H Zhu, T Ge, Z Wang, C Zhang - Stem cell reviews and reports, 2021 - Springer
Diabetes mellitus (DM), a chronic disorder of carbohydrate metabolism, is characterized by
the unbridled hyperglycemia resulted from the impaired ability of the body to either produce …

Thrombin preconditioning improves the therapeutic efficacy of mesenchymal stem cells in severe intraventricular hemorrhage induced neonatal rats

SY Jung, YE Kim, WS Park, SY Ahn, DK Sung… - International Journal of …, 2022 - mdpi.com
Severe intraventricular hemorrhage (IVH) remains a major cause of high mortality and
morbidity in extremely preterm infants. Mesenchymal stem cell (MSC) transplantation is a …

Culture of iPSCs Derived Pancreatic β‐Like Cells In Vitro Using Decellularized Pancreatic Scaffolds: A Preliminary Trial

J Wan, Y Huang, P Zhou, Y Guo, C Wu… - BioMed research …, 2017 - Wiley Online Library
Diabetes mellitus is a disease which has affected 415 million patients in 2015. In an effort to
replace the significant demands on transplantation and morbidity associated with …