Human monkeypox is a viral zoonosis endemic to West and Central Africa that has recently
generated increased interest and concern on a global scale as an emerging infectious …

ABSTRACT Introduction Tecovirimat (TPOXX®; ST-246) was approved for the treatment of
symptomatic smallpox by the USFDA in July of 2018 and has been stockpiled by the US …

Background Cases of human monkeypox are rarely seen outside of west and central Africa.
There are few data regarding viral kinetics or the duration of viral shedding and no licensed …

Background Smallpox was declared eradicated in 1980, but variola virus (VARV), which
causes smallpox, still exists. There is no known effective treatment for smallpox; therefore …

As people around the world regard 2020 as the year of COVID-19, the medical community
considers this year to be the second-best year, shared with the year 1996, with respect to the …

The zoonosis human monkeypox (MPX) was discovered in 1970, twelve years after the
discovery of monkeypox virus (MPXV) in a Danish laboratory in 1958. Historically confined …

Abstract Infection caused by Monkeypox Virus (MPVX) has small rodents as its natural
reservoir and both monkeys and humans are occasional hosts. The causative agent is an …

Mpox virus is an emergent human pathogen. While it is less lethal than smallpox, it can still
cause significant morbidity and mortality. In this review, we explore 3 antiviral agents with …

Abstract 2017 marked the 30th anniversary of the approval of zidovudine (AZT) as the first
HIV/AIDS therapy. Since then, more than eighty antiviral drugs have received FDA approval …

Since the eradication of smallpox approximately 39 years ago, monkeypox virus remains the
most pathogenic poxvirus, being mainly restricted to Central and West Africa. Before 1970 …