Terpenoids, Cannabimimetic Ligands, beyond the Cannabis Plant

ECD Gonçalves, GM Baldasso, MA Bicca, RS Paes… - Molecules, 2020 - mdpi.com
Medicinal use of Cannabis sativa L. has an extensive history and it was essential in the
discovery of phytocannabinoids, including the Cannabis major psychoactive compound—Δ9 …

Terpenes/Terpenoids in Cannabis: Are They Important?

LO Hanuš, Y Hod - Medical Cannabis and Cannabinoids, 2020 - karger.com
Cannabis sativa plant has not only cannabinoids as crucial compounds but also the other
compounds that play important role as synergistic and/or entourage compound …

[HTML][HTML] Models for cytotoxicity screening of antileishmanial drugs: what has been done so far?

MBC Brioschi, EM Coser, AC Coelho… - International Journal of …, 2022 - Elsevier
A growing number of studies have demonstrated the in vitro potential of an impressive
number of antileishmanial candidates in the past years. However, the lack of uniformity …

Bacillus velezensis HY19 as a sustainable preservative in post-harvest citrus (Citrus reticulata Blanco L.) fruit management

S Li, J Hu, S Ning, W Li, R Jiang, J Huang, Y Li - Food Control, 2024 - Elsevier
Citrus fruit post-harvest decay has caused economic loss for fruit-dependent industries
worldwide in recent decades. However, bio-preservatives offer a promising and sustainable …

Extraction of Camphor Tree Essential Oil by Steam Distillation and Supercritical CO2 Extraction

H Zhang, T Huang, X Liao, Y Zhou, S Chen, J Chen… - Molecules, 2022 - mdpi.com
The essential oil extracted from Cinnamomum camphora leaves is a mixture of volatile
compounds, mainly terpenes, and is widely used in medicine, perfume and chemical …

[HTML][HTML] Membrane dynamics in Leishmania amazonensis and antileishmanial activities of β-carboline derivatives

L Alonso, JC de Paula, P Baréa, MH Sarragiotto… - … et Biophysica Acta (BBA …, 2021 - Elsevier
Two β-carboline compounds, 8i and 6d, demonstrated in vitro antileishmanial activity
against Leishmania (L.) amazonensis promastigotes similar to that of miltefosine (MIL) …

Antileishmanial activity of the chalcone derivative LQFM064 associated with reduced fluidity in the parasite membrane as assessed by EPR spectroscopy

L Alonso, R Menegatti, RS Gomes, ML Dorta… - European Journal of …, 2020 - Elsevier
A novel chalcone derivative, LQFM064, demonstrated antileishmanial activity against
Leishmania (L.) amazonensis, with an IC 50 value of~ 10 μM for the promastigote form …

Antileishmanial activities of three chalcone derivatives and their association with plasma membrane rigidity as assessed by EPR spectroscopy

EN Borges, L Alonso, MB Silveira, RB Balbinot… - Journal of Molecular …, 2023 - Elsevier
Novel chalcone-like compounds, LQFM332 (4), LQFM333 (5), and LQFM341 (6), were
synthesized and their activity against Leishmania (L.) amazonensis was evaluated and …

Mechanism of cis-Nerolidol-Induced Bladder Carcinoma Cell Death

M Glumac, V Čikeš Čulić, I Marinović-Terzić, M Radan - Cancers, 2023 - mdpi.com
Simple Summary The aim of this study was to determine the antitumor activity of nerolidol, a
naturally occurring sesquiterpene alcohol, in two bladder carcinoma cell lines and to …

The interaction of a thiosemicarbazone derived from R-(+)-limonene with lipid membranes

CA Marquezin, CMA de Oliveira, F Vandresen… - Chemistry and Physics …, 2021 - Elsevier
As a potential drug, 2-nitrobenzaldehyde-thiosemicarbazone (2-TSC), a thiosemicarbazone
derived from the terpene R-(+)-limonene, was studied through calorimetric and …